Annals of Emergency Medicine
Volume 40, Issue 5 , Pages 453-460 , November 2002

Sex and acute stroke presentation

Received 14 December 2001 ,Revised 23 May 2002 ,Accepted 14 June 2002.

References 

  1. American Stroke Association . About stroke. Available at http://www.strokeassociation.org/presenter.jhtmlNovember 20, 2001; Accessed
  2. Jones TH, Morawetz RB, Crowell RM, et al.  Thresholds of focal cerebral ischemia in awake monkeys. J Neurosurg. 1987;54:773–782
  3. Kaplan B, Brint S, Tanabe J, et al.  Temporal thresholds for neocortical infarction in rats subjected to reversible focal cerebral ischemia. Stroke. 1991;22:1032–1039
  4. Memezawa H, Smith ML, Kiesjo BK. Penumbral tissues salvaged by reperfusion following middle cerebral artery occlusion in rats. Stroke. 1992;23:552–559
  5. Marler JR, Tilley BC, Lu M, et al.  Early stroke treatment associated with better outcome. Neurology. 2000;55:1649–1655
  6. del Zoppo G, Higashida R, Furlan A, et al.  PROACT: a phase II randomized trial of recombinant prourokinase by direct arterial delivery in acute middle cerebral artery stroke. Stroke. 1998;29:4–11
  7. National Institute of Neurological Disorders, Stroke rt-PA Stroke Study Group . Tissue plasminogen activator for acute ischemic stroke. N Engl J Med. 1995;333:1581–1587
  8. Wyller TB. Stroke and gender. J Gender Specific Med. 1999;2:41–45
  9. Wyller TB, Dodring KN, Sveen U, et al.  Are there gender differences in functional outcome after stroke?. Clin Rehabil. 1997;11:171–175
  10. Morgenstern LB, Spears WD, Goff DC, et al.  African Americans and women have the highest stroke mortality in Texas. Stroke. 1197;28:15–18
  11. Holroyd-Leduc JM, Kapral MK, Austin PC, et al.  Sex differences and similarities in the management and outcome of stroke patients. Stroke. 2000;31:1833–1837
  12. Menon SC, Pandey DK, Morgenstern LB. Critical factors determining access to acute stroke care. Neurology. 1998;51:427–432
  13. Engelstein E, Margulies J, Jeret JS. Lack of t-PA use for acute ischemic stroke in a community hospital: high incidence of exclusion criteria. Am J Emerg Med. 2000;18:257–260
  14. Wein TH, Staub L, Felberg R, et al.  Activation of emergency medical services for acute stroke in a nonurban population: the TLL Temple Foundation Stroke Project. Stroke. 2000;31:1925–1928
  15. Burgin WS, Staub L, Chan W, et al.  Acute stroke care in nonurban emergency departments. Neurology. 2001;57:2006–2012
  16. Morgenstern LB, Staub L, Chan W, et al.  Improving delivery of acute stroke therapy: the TLL Temple Foundation Stroke Project. Stroke. 2002;33:160–166
  17. Morgenstern LB, Wein TH, Smith MA, et al.  Comparison of stroke hospitalization rates among Mexican-Americans and non-Hispanic whites. Neurology. 2000;54:2000–2002
  18. Tuomilehto J, Sarti C, Narva E, et al.  The FINMONICA Stroke Register: community based stroke registration and analysis of stroke incidence in Finland. Am J Epidemiol. 1992;135:1259–1270
  19. Asplund K, Tuomilheto J, Stegmayr B, et al.  Diagnostic criteria and quality control of the registration of stroke events in the MONICA project. Acta Med Scand. 1988;728(suppl):26–39
  20. DiCarlo A, Launer J, Breteler MMB, et al.  Frequency of stroke in Europe: a collaborative study of population-based cohorts. Neurology. 2000;54(suppl 5):S28–S33
  21. Thorvaldsen P, Asplund K, Kuulasmaa K, et al.  Stroke incidence, case fatality, and mortality in the WHO MONICA Project. Stroke. 1995;26:361–367
  22. Sudlow CL, Warlow CP. Comparable studies of the incidence of stroke and its pathologic types: results from an international collaboration (International Stroke Incidence Collaboration). Stroke. 1997;28:491–499
  23. Thompson DW, Furlan AJ. Clinical epidemiology of stroke. Neuroepidemiology. 1996;14:309–315
  24. Giampaoli S. Epidemiology of major age-related diseases in women compared to men. Aging. 2000;12:93–105
  25. Guralnik JM, Balfour JL, Volpato S. The ratio of older women to men: historical perspectives and cross-national comparisons. Aging. 2000;12:321–322
  26. Allen CMC. Clinical diagnosis of the acute stroke syndrome. QJM. 1983;208:515–523
  27. Weir CJ, Murray GD, Adams FG, et al.  Poor accuracy of stroke scoring systems for differential clinical diagnosis of intracranial haemorrhage and infarction. Lancet. 1994;344:999–1002
  28. Besson G, Robert C, Hommel M, et al.  Is it clinically possible to distinguish nonhemorrhagic infarct form hemorrhagic stroke?. Stroke. 1995;26:1205–1209
  29. Heim LJ, Brunsell SC. Heart disease in women. Prim Care. 2000;27:741–766
  30. Leape LL, Hilborne LH, Bell R, et al.  Underuse of cardiac procedures: do women, ethnic minorities, and the uninsured fail to receive needed reascularization?. Ann Intern Med. 1999;130:183–192
  31. Maynard C, Beshansky JR, Griffith JL, et al.  Influence of sex on the use of cardiac procedures in patients presenting to the emergency department. Circulation. 1996;94(suppl):II93–II98
  32. Schulman KA, Berlin JA, Harless W, et al.  The effect of race and sex on physicians' recommendations for cardiac catheterization. N Engl J Med. 1999;340:618–626
  33. Vacek JL, Rosamond TL, Kramer PH, et al.  Sex-related differences in patients undergoing direct angioplasty for acute myocardial infarction. Am Heart J. 1993;126:521–525
  34. Tobin JN, Wassertheil-Smoller S, Wexler JP, et al.  Sex bias in considering coronary bypass surgery. Ann Intern Med. 1987;107:19–25
  35. Ramani S, Byrne-Logan S, Freund KM, et al.  Gender differences in the treatment of cerebrovascular disease. J Am Geriatr Soc. 2000;48:741–745
  36. Harper GD, Haigh RA, Potter JF, et al.  Factors delaying hospital admission after stroke in Leicestershire. Stroke. 1992;23:835–838
  37. Kothari R, Jauch E, Broderick J, et al.  Acute stroke: delays to presentation and emergency department evaluation. Ann Emerg Med. 1999;33:3–8
  38. Geffner D, Lago A, Tembl J, et al.  Delayed hospitalization of the patient with acute stroke. Rev Neurol. 1998;27:947–951
  39. Goldstein LB, Edwards MG, Wood DP. Delay between stroke onset and emergency department evaluation. Neuroepidemiology. 2001;20:196–200
  40. Davalos A, Castillo J, Martinez-Vila E. Delay in neurological attention and stroke outcome. Cerebrovascular Diseases Study Group of the Spanish Society of Neurology. Stroke. 1995;26:2233–2237
  41. Kothari R, Sauerbeck , Jauch E, et al.  Patients' awareness of stroke signs, symptoms, and risk factors. Stroke. 1997;28:1871–1875
  42. Azzimondi G, Bassein L, Fiorani L, et al.  Variables associated with hospital arrival time after stroke: effect of delay on the clinical efficiency of early treatment. Stroke. 1997;28:537–542
  43. Smith MA, Doliszny KM, Shahar E, et al.  Delayed hospital arrival for acute stroke: the Minnesota Stroke Survey. Ann Intern Med. 1998;129:190–196

 Supported by a grant from the TLL Temple Foundation.

☆☆ Address for reprints: Lewis B. Morgenstern, MD, University of Michigan Health System, TC 1920/0316, 1500 East Medical Center Drive, Ann Arbor, MI 48109-0316; 734-615-7390, fax 734-936-8763; E-mail lmorgens@umich.edu

PII: S0196-0644(02)00076-8

doi: 10.1067/mem.2002.128682

Annals of Emergency Medicine
Volume 40, Issue 5 , Pages 453-460 , November 2002