Annals of Emergency Medicine
Volume 54, Issue 6 , Pages 763-768 , December 2009

The Prevalence and Factors Associated With QTc Prolongation Among Emergency Department Patients

Presented as a poster at the Society of Academic Emergency Medicine annual meeting, May 2008, Washington DC.

Received 20 November 2008 ,Revised 4 March 2009 ,Accepted 19 March 2009.

References 

  1. Moss AJ. Long QT syndrome. JAMA. 2003;289:2041–2044
  2. Bednar MM, Harrigan EP, Anziano RJ, et al. The QT interval. Prog Cardiovasc Dis. 2001;43:1–45
  3. Schouten EG, Dekker JM, Meppelink P, et al. QT interval prolongation predicts cardiovascular mortality in an apparently health population. Circulation. 1991;84:1516–1523
  4. Khan IA. Long QT syndrome: diagnosis and management. Am Heart J. 2002;143:7–14
  5. Moss AJ, Zareba W, Hall WJ, et al. Effectiveness and limitations of beta-blocker therapy in congenital long-QT syndrome. Circulation. 2000;101:616–623
  6. Golzari H, Dawson NV, Speroff T. Prolonged QTc intervals on admission electrocardiograms: prevalence and correspondence with admission electrolyte abnormalities. Conn Med. 2007;71:389–397
  7. Smith SW, Martel M, Chase P, et al. QT lengthening after administration of droperidol. Acad Emerg Med. 2002;9:374–375
  8. Yang T, Roden DM. Extracellular potassium modulation of drug block of IKr (Implications for torsades de pointes and reverse use-dependence). Circulation. 1996;93:407–411
  9. Passman R, Kadish A. Polymorphic ventricular tachycardia, long QT syndrome and torsades de pointes. Med Clin North Am. 2001;85:321–341
  10. Priori SG, Aliot E, Blomstrom-Lundqvist C, et al. Task Force on Sudden Cardiac Death of the European Society of Cardiology. Eur Heart J. 2001;22:1374–1450
  11. Silka M, Kron J, Dunnigan A, et al. Sudden cardiac death and the use of implantable cardioverter-defibrillators in pediatric patients. Circulation. 1993;87:800–807
  12. Goldstein DS. The electrocardiogram in stroke: relationship to pathophysiological type and comparison with prior tracings. Stroke. 1979;10:253–259
  13. Zeltser D, Justo D, Halkin A, et al. Torsades de pointes due to noncardiac drugs: most patients have easily identifiable risk factors. Medicine. 2003;82:282–290
  14. Breidthardt T, Christ M, Matti M, et al. QRS and QTc interval prolongation in the prediction of long-term mortality of patients with acute destabilised heart failure. Heart. 2007;93:1093–1097
  15. Nakanishi S, Yamada M, Nobuaki H, et al. Relation between QT duration and mortality in an elderly Japanese population. Am J Cardiol. 2004;93:1182–1185
  16. Robbins J, Nelson JC, Rautaharju PM, et al. The association between the length of the QT interval and mortality in the Cardiovascular Health Study. Am J Med. 2003;11:732–734
  17. Schouten EG, Dekker JM, Meppelink FJ, et al. QT interval prolongation predicts cardiovascular mortality in an apparently healthy population. Circulation. 1991;84:1516–1523
  18. Luo S, Michler K, Johnston P, et al. A comparison of commonly used QT correction formulae: the effect of heart rate on the QTc of normal ECGs. J Electrocardiol. 2004;37(suppl):81–90
  19. Golberger AL. Clinical Electrocardiography: A Simplified Approach. In: 7th ed.. Philadelphia, PA: Mosby Elsevier; 2006;p. 9–15

 Provide feedback on this article at the journal's Web site, www.annemergmed.com.

 Supervising editors: Deborah B. Diercks, MD; Michael L. Callaham, MD

 Author contributions: MWS conceived the study. MWS, PHA, MH, and ABW designed the study. MWS and PHA supervised the data collection. MWS, PHA, STCC, BWW, and GDF collected the study data. MH provided statistical advice for the study. PHA and MH analyzed the data. MWS and PHA drafted the article. All authors contributed to the manuscript revision. MWS takes responsibility for the paper as a whole.

 Funding and support: By Annals policy, all authors are required to disclose any and all commercial, financial, and other relationships in any way related to the subject of this article that might create any potential conflict of interest. The authors have stated that no such relationships exist. See the Manuscript Submission Agreement in this issue for examples of specific conflicts covered by this statement.

 Reprints not available from the authors.

 Publication date: Available online May 6, 2009.

PII: S0196-0644(09)00283-2

doi: 10.1016/j.annemergmed.2009.03.021

Annals of Emergency Medicine
Volume 54, Issue 6 , Pages 763-768 , December 2009

Article Tools