Annals of Emergency Medicine
Volume 55, Issue 4 , Pages 345-351 , April 2010

Hydroxocobalamin and Sodium Thiosulfate Versus Sodium Nitrite and Sodium Thiosulfate in the Treatment of Acute Cyanide Toxicity in a Swine (Sus scrofa) Model

Presented at the Society for Academic Emergency Medicine national meeting, May 2009, New Orleans, LA.

  • Vikhyat S. Bebarta, MD, Maj, MC, USAF

      Affiliations

    • Medical Toxicology, University of Texas Health Sciences Center, San Antonio, TX
    • Wilford Hall Medical Center, University of Texas Health Sciences Center, San Antonio, TX
    • Corresponding Author InformationAddress for reprints: Vikhyat S. Bebarta, MD, Maj, MC, USAF, 23239 Crest View Way, San Antonio, TX 78236; 210-292-3908, fax 210-292-7649
    • ,
  • David A. Tanen, MD, CDR, MC, USN

      Affiliations

    • Department of Emergency Medicine, Naval Medical Center, San Diego, CA
    • ,
  • Julio Lairet, DO, Maj, MC, USAF

      Affiliations

    • Department of Emergency Medicine, University of Texas Health Sciences Center, San Antonio, TX
    • ,
  • Patricia S. Dixon, MS

      Affiliations

    • Clinical Research Division, University of Texas Health Sciences Center, San Antonio, TX
    • ,
  • Sandra Valtier, PhD

      Affiliations

    • Clinical Research Division, University of Texas Health Sciences Center, San Antonio, TX
    • ,
  • Anneke Bush, ScD, MHS

      Affiliations

    • Clinical Research Division, University of Texas Health Sciences Center, San Antonio, TX

Received 24 June 2009 ,Revised 4 September 2009 ,Accepted 18 September 2009.

References 

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 Supervising editor: E. Martin Caravati, MD, MPH

 Author contributions: VSB and DAT conceived and designed the trial. VSB obtained research funding, and VSB, JL, PSD, and SV performed the study. VSB, JL, PSD, SV, and AB supervised the conduct of the study and data collection. AB provided statistical advice on study design and analyzed the data. VSB and DAT drafted the article, and all authors contributed substantially to its revision. VSB takes responsibility for the paper as a whole.

 Funding and support: By Annals policy, all authors are required to disclose any and all commercial, financial, and other relationships in any way related to the subject of this article that might create any potential conflict of interest. See the Manuscript Submission Agreement in this issue for examples of specific conflicts covered by this statement. The US Air Force Office of the Surgeon General funded this study. No other funding was used.

 Publication date: Available online November 27, 2009.

 The views expressed in this article are those of the authors and do not reflect the official policy or position of the Department of the US Air Force, Department of Defense, or the US government.

 Please see page 346 for the Editor's Capsule Summary of this article.

 Provide feedback on this article at the journal's Web site, www.annemergmed.com.

PII: S0196-0644(09)01558-3

doi: 10.1016/j.annemergmed.2009.09.020

Annals of Emergency Medicine
Volume 55, Issue 4 , Pages 345-351 , April 2010

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