Annals of Emergency Medicine
Volume 39, Issue 3 , Pages 254-257 , March 2002

Serum cleaved tau protein levels and clinical outcome in adult patients with closed head injury

Presented in part at the American College of Emergency Physicians Scientific Assembly, Las Vegas, NV, October 1999.

Received 21 December 2000 ,Revised 26 September 2001 ,Accepted 11 October 2001.

References 

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  2. Rothoerl R, Woertgen C, Holzschuh M, et al.  S-100 Levels after minor and major head injury. J Trauma. 1998;45:765–767
  3. Woertgen C, Rothoerl R, Metz C, et al.  Comparison of serial S-100 and NSE serum measurements after severe head injury. Acta Neurochir (Wien. 1997;139:1161–1165
  4. Yamazaki Y, Yada K, Morii S, et al.  Diagnostic significance of serum neuron-specific enolase and myelin basic protein assay in patients with acute head injury. Surg Neurol. 1995;43:267–271
  5. Raabe A, Grolms C, Keller M, et al.  Correlation of computed tomography findings and serum brain damage markers following severe head injury. Acta Neurochir (Wien). 1998;140:787–792
  6. Bernstein D, Wong M, Ogilvie J, et al. Electrophysiological evidence for impaired cognition 8 years after mild head injury. Paper presented at: the Society for Neuroscience annual meeting; November 1998; Los Angeles, CA.
  7. Waterloo K, Ingebrigsten T, Romner B. Neuropsychological function in patients with increased serum levels of protein S-100 after minor head injury. Acta Neurochir (Wien). 1997;139:26–32
  8. Woertgen C, Rothoerl R, Metz C, et al.  Comparison of clinical, radiologic, and serum marker as prognostic factors after severe head injury. J Trauma. 1999;47:1126–1130
  9. Zemlan F, Rosenberg W, Luebbe P, et al.  Quantification of axonal damage in traumatic brain injury: affinity purification and characterization of cerebrospinal fluid tau proteins. J Neurochem. 1999;72:741–750
  10. Zemlan F, Jauch E, Smith M, et al.  Biomarker for quantifying neuronal damage across neurologic disorders [abstract]. Abstract presented at: the Society for Neuroscience annual meeting; November 2000; New Orleans, LA, J Neurotrauma. 2000;17:946

☆ Author contributions are provided at the end of this article.

☆☆ Supported by a Resident Research Grant from the University of Cincinnati Department of Emergency Medicine (GJS).

★ Address for reprints: George J. Shaw, MD, PhD, Department of Emergency Medicine, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267-0769; 513-558-5281,fax 513-558-5891; shawge@ucmail.uc.edu

PII: S0196-0644(02)20408-4

doi: 10.1067/mem.2002.121214

Annals of Emergency Medicine
Volume 39, Issue 3 , Pages 254-257 , March 2002

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