Annals of Emergency Medicine
Volume 39, Issue 3 , Pages 342-343 , March 2002

Rule out TBI? Serum markers for traumatic brain injury

References 

  1. Haydel MJ, Preston CA, Mills TJ, et al.  Indications for computed tomography in patients with minor head injury. N Engl J Med. 2000;343:100–105
  2. Stiell IG, Wells GA, Vandemheen K, et al.  The Canadian CT Head Rule for patients with minor head injury. Lancet. 2001;357:1391–1396
  3. Ingebrigtsen T, Waterloo K, Marup-Jensen S, et al.  Quantification of post-concussion symptoms 3 months after minor head injury in 100 consecutive patients. J Neurol. 1998;245:609–612
  4. Bazarian JJ, Atabaki S. Predicting postconcussion syndrome after minor traumatic brain injury. Acad Emerg Med. 2001;8:788–795
  5. Servadei F, Teasdale G, Merry G. Defining acute mild head injury in adults: a proposal based on prognostic factors, diagnosis, and management. J Neurotrauma. 2001;18:657–664
  6. Shaw GJ, Jauch EC, Zelman FP. Serum cleaved tau protein levels and clinical outcome in adult patients with closed head injury. Ann Emerg Med. 2002;39:254–257
  7. Raabe A, Grolms C, Seifert V. Serum markers of brain damage and outcome prediction in patients after severe head injury. Br J Neurosurg. 1999;13:56–59
  8. de Kruijk JR, Leffers P, Menheere PPCA, et al.  S-100B and neuron-specific enolase in serum of mild traumatic brain injury patients. Acta Neurol Scand. 2001;103:175–179
  9. Ingebrigtsen T, Romner B, Marup-Jensen S, et al.  The clinical value of serum S-100 protein measurements in minor head injury: a Scandinavian multicentre study. Brain Injury. 2000;14:1047–1055
  10. Woertgen C, Rothoerl RD, Metz C, et al.  Comparison of clinical, radiologic, and serum marker as prognostic factors after severe head injury. J Trauma. 1999;47:1126–1130
  11. Ingebrigtsen T, Waterloo K, Jacobsen EA, et al.  Traumatic brain damage in minor head injury: relation of serum S-100 protein measurements to magnetic resonance imaging and neurobehavioral outcome. Neurosurgery. 1999;45:468–476
  12. Raabe A, Grolms C, Sorge O, et al.  Serum S-100B protein in severe head injury. Neurosurgery. 1999;45:477–483
  13. Herrmann M, Jost S, Kutz S, et al.  Temporal profile of release of neurobiochemical markers of brain damage after traumatic brain injury is associated with intracranial pathology demonstrated by cranial computerized tomography. J Neurotrauma. 2000;17:113–121
  14. Herrmann M, Curio N, Jost S, et al.  Release of biochemical markers of damage to neuronal and glial brain tissue is associated with short and long term neuropsychological outcome after traumatic brain injury. J Neurol Neurosurg Psychiatry. 2001;70:95–100
  15. Voller B, Auff E, Schnider P, et al.  To do or not to do? Magnetic resonance imaging in mild traumatic brain injury. Brain Injury. 2001;15:107–115

 Reprints not available from the author. Address for correspondence: Robert W. Neumar, MD, PhD, Department of Emergency Medicine, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104; 215-898-4960, fax 215-573-5140; E-mail: rneumar@mail.med.upenn.edu.

PII: S0196-0644(02)70703-8

doi: 10.1067/mem.2002.122007

Annals of Emergency Medicine
Volume 39, Issue 3 , Pages 342-343 , March 2002