Annals of Emergency Medicine
Volume 48, Issue 4 , Pages 441-447 , October 2006

Identifying Hospitalized Infants Who Have Bronchiolitis and Are at High Risk for Apnea

Presented in part at the Pediatric Academic Societies meeting, April 2001, Baltimore, MD.

  • Ben M. Willwerth, MD, MMSc

      Affiliations

    • Division of Emergency Medicine, Children’s Hospital Boston, Boston, MA
  • ,
  • Marvin B. Harper, MD

      Affiliations

    • Division of Emergency Medicine, Children’s Hospital Boston, Boston, MA
    • Division of Infectious Diseases, Children’s Hospital Boston, Boston, MA
    • Corresponding Author InformationAddress for correspondence: Marvin Harper, MD, Children’s Hospital Boston, Division of Emergency Medicine, Main 1, 300 Longwood Avenue, Boston, MA 02115; 617-355-6624, fax 617-731-3279
  • ,
  • David S. Greenes, MD

      Affiliations

    • Division of Emergency Medicine, Children’s Hospital Boston, Boston, MA

Received 3 March 2006 ,Accepted 13 March 2006.

References 

  1. Shay D, Holman R, Newman R, et al. Bronchiolitis-associated hospitalizations among US children, 1980-1996. JAMA. 1999;282:1440–1446
  2. Bruhn F, Mokrohisky S, McIntosh K. Apnea associated with respiratory syncytial virus infection in young infants. J Pediatr. 1977;90:382–386
  3. Hall C, Kopelman A, Douglas R, et al. Neonatal respiratory syncytial virus infection. N Engl J Med. 1979;300:393–396
  4. Anas N, Boettrich C, Hall C, et al. The association of apnea and respiratory syncytial virus infection in infants. J Pediatr. 1982;101:65–68
  5. Kneyber M, Brandenburg A, de Groot R, et al. Risk factors for respiratory syncytial virus associated apnoea. Eur J Pediatr. 1998;157:331–335
  6. Church N, Anas N, Hall C, et al. Respiratory syncytial virus-related apnea in infants. Am J Dis Child. 1984;138:247–250
  7. Schuh S, Coates A, Binnie R, et al. Efficacy of oral dexamethasone in outpatients with acute bronchiolitis. J Pediatr. 2002;140:27–32
  8. Papadopolous N, Moustaki M, Tsolia M, et al. Association of rhinovirus infection with increased disease severity in acute bronchiolitis. Am J Respir Crit Care Med. 2002;165:1285–1289
  9. Colditz P, Henry R, DeSilva L. Apnoea and bronchiolitis due to respiratory syncytial virus. Aust Paediatr J. 1982;18:53–54
  10. Meert K, Heidemann S, Abella B, et al. Does prematurity alter the course of respiratory syncytial virus infection?. Crit Care Med. 1990;18:1357–1359

 Supervising editor: Steven M. Green, MD

 Author contributions: BMW, MBH, and DSG conceived and designed the study. BMW and MBH performed data collection. DSG undertook data collection to provide interrater reliability statistics. BMW conducted initial data analysis. MBH and DSG provided statistical advice on study design and thoroughly reviewed data analysis. BMW drafted the manuscript, and all authors contributed substantially to its revision. BMW takes responsibility for the paper as a whole.

 Funding and support: The authors report this study did not receive any outside funding or support.

 Reprints not available from the authors.

PII: S0196-0644(06)00418-5

doi: 10.1016/j.annemergmed.2006.03.021

Annals of Emergency Medicine
Volume 48, Issue 4 , Pages 441-447 , October 2006