Annals of Emergency Medicine
Volume 49, Issue 1 , Pages 37-44 , January 2007

Delayed Fluid Resuscitation in Hemorrhagic Shock Induces Proinflammatory Cytokine Response

  • Chien-Chang Lee, MD, MSc

      Affiliations

    • Department of Emergency Medicine, National Taiwan University Hospital, and National Taiwan University, College of Medicine, Taipei, Taiwan
  • ,
  • I.-Jing Chang, MD

      Affiliations

    • Institute of Preventive Medicine, School of Public Health, National Taiwan University and Taipei City Hospital, Renai Branch, Taipei, Taiwan
  • ,
  • Zui-Shen Yen, MD, MPH

      Affiliations

    • Department of Emergency Medicine, National Taiwan University Hospital, and National Taiwan University, College of Medicine, Taipei, Taiwan
  • ,
  • Chiung-Yuan Hsu, MD

      Affiliations

    • Department of Emergency Medicine, National Taiwan University Hospital, and National Taiwan University, College of Medicine, Taipei, Taiwan
  • ,
  • Shey-Ying Chen, MD

      Affiliations

    • Department of Emergency Medicine, National Taiwan University Hospital, and National Taiwan University, College of Medicine, Taipei, Taiwan
  • ,
  • Chan-Ping Su, MD

      Affiliations

    • Department of Emergency Medicine, National Taiwan University Hospital, and National Taiwan University, College of Medicine, Taipei, Taiwan
  • ,
  • Wen-Chu Chiang, MD

      Affiliations

    • Department of Emergency Medicine, National Taiwan University Hospital, and National Taiwan University, College of Medicine, Taipei, Taiwan
  • ,
  • Shyr-Chyr Chen, MD, MBA

      Affiliations

    • Department of Emergency Medicine, National Taiwan University Hospital, and National Taiwan University, College of Medicine, Taipei, Taiwan
    • Corresponding Author InformationAddress for reprints: Shyr-Chyr Chen, MD, MBA, Department of Emergency Medicine, National Taiwan University Hospital and National Taiwan University, College of Medicine, No 7, Chung-Shan South Road, Taipei, Taiwan 100
  • ,
  • Wen-Jone Chen, MD, PhD

      Affiliations

    • Department of Emergency Medicine, National Taiwan University Hospital, and National Taiwan University, College of Medicine, Taipei, Taiwan

Received 9 January 2006 ,Revised 4 May 2006 ,Accepted 11 May 2006.

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 Supervising editor: Stephen R. Thom, MD, PhDAuthor contributions: S-CC was the principal investigator and was responsible for the study design, managing and monitoring the study, and contributing to analysis and interpretation. C-CL wrote the article. C-CL, I-JC, Z-SY, C-YH, S-YC helped with design, analysis and interpretation of data, monitoring the study, and editing the article. C-PS, W-CC, and W-JC helped refine the study design, contributed to analysis and interpretation, and helped edit the article. S-CC takes responsibility for the paper as a whole.Funding and support: The authors report this study was supported by National Science Council grants NSC92-2314-002-282 and NSC90-2314-002-334.

PII: S0196-0644(06)01016-X

doi: 10.1016/j.annemergmed.2006.05.031

Annals of Emergency Medicine
Volume 49, Issue 1 , Pages 37-44 , January 2007