Annals of Emergency Medicine
Volume 50, Issue 3 , Pages 221-230 , September 2007

Cluster-Randomized Trial to Improve Antibiotic Use for Adults With Acute Respiratory Infections Treated in Emergency Departments

Presented at the 29th annual meeting of the Society of General Internal Medicine, April 2006, Los Angeles, CA; and at the annual meeting of the Society for Academic Emergency Medicine, May 2006, San Francisco, CA.

  • Joshua P. Metlay, MD, PhD

      Affiliations

    • Center for Health Equity Research and Promotion, VA Medical Center, Philadelphia, PA
    • Division of General Internal Medicine and the Centers for Education and Research on Therapeutics, University of Pennsylvania School of Medicine, Philadelphia, PA
    • Corresponding Author InformationAddress for correspondence: Joshua P. Metlay, MD, PhD, University of Pennsylvania School of Medicine, 712 Blockley Hall, 423 Guardian Drive, Philadelphia, PA 19104; 215-898-1484, fax 215-573-0198.
    • ,
  • Carlos A. Camargo Jr, MD, DrPH

      Affiliations

    • Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA
    • ,
  • Thomas MacKenzie, MD, MSPH

      Affiliations

    • Denver Health Medical Center, Denver, CO
    • ,
  • Charles McCulloch, PhD

      Affiliations

    • Department of Epidemiology and Biostatistics, University of California, San Francisco, CA
    • ,
  • Judith Maselli, MSPH

      Affiliations

    • Division of General Internal Medicine, Department of Medicine, University of California, San Francisco, CA.
    • ,
  • Sara K. Levin, BA

      Affiliations

    • Division of General Internal Medicine, Department of Medicine, University of California, San Francisco, CA.
    • ,
  • Ayanna Kersey, MPH

      Affiliations

    • Center for Health Equity Research and Promotion, VA Medical Center, Philadelphia, PA
    • ,
  • Ralph Gonzales, MD, MSPH

      Affiliations

    • Department of Epidemiology and Biostatistics, University of California, San Francisco, CA
    • Division of General Internal Medicine, Department of Medicine, University of California, San Francisco, CA.
    • ,
  • IMPAACT Investigators

      Affiliations

    • All members are listed in the Appendix.

Received 20 November 2006 ,Revised 9 March 2007 ,Accepted 16 March 2007.

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 Supervising editor: Gregory J. Moran, MDAuthor contributions: JPM, CAC, TM, CM, and RG were responsible for study conception and design. JPM, JM, SKL, AK, and RG were responsible for acquisition of data and administrative, technical, or material support. JPM, CAC, TM, CM, JM, and RG conducted analysis and interpretation of data. JPM, CAC, CM, JM, and RG were responsible for drafting of the article and statistical analysis. JPM, CAC, TM, and RG obtaining funding. All authors provided critical revision of the manuscript. JPM and RG were responsible for study supervision. JPM and RG takes responsibility for the paper as a whole.Conflicts of interest: Dr. Metlay has served as a scientific consultant or received unrestricted educational funds from Aventis Pharmaceuticals and Roche Pharmaceuticals. Dr. Gonzales served as a consultant for Abbott Laboratories, Inc. to study C-reactive protein levels as a potential diagnostic test for outpatients with community-acquired pneumonia. Dr. Camargo has received financial support for participation in conferences, consulting, and medical research from the following industry sponsors with an interest in respiratory infections: Abbott, Aventis, Aventis Pasteur, GlaxoSmithKline, MedImmune, and Merck. None of the other authors have any conflicts of interest or financial disclosures.Funding and support: By Annals policy, all authors are required to disclose any and all commercial, financial, and other relationships in any way related to the subject of this article, that may create any potential conflict of interest. See the Manuscript Submission Agreement in this issue for examples of specific conflicts covered by this statement. This study was funded by the Translating Research into Practice initiative, jointly sponsored by the Agency for Healthcare Research and Quality (1 R01 HS013915) and the Health Services Research and Development Service of the Department of Veterans Affairs (AVA-03-239). The funding agencies had no role in the design and conduct of the study; collection management, analysis, and interpretation of the data; or preparation, review, or approval of the article.Available online May 23, 2007.Reprints not available from the authors.

PII: S0196-0644(07)00383-6

doi: 10.1016/j.annemergmed.2007.03.022

Annals of Emergency Medicine
Volume 50, Issue 3 , Pages 221-230 , September 2007

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