Annals of Emergency Medicine
Volume 51, Issue 3 , Pages 221-229, March 2008

Increased Blood Pressure in the Emergency Department: Pain, Anxiety, or Undiagnosed Hypertension?

Presented as a poster at the Society of Academic Emergency Medicine annual meeting, May 2006, San Francisco, CA; and the Society of Academic Emergency Medicine annual meeting, May 2007, Chicago, IL.

  • Paula Tanabe, PhD, MPH

      Affiliations

    • Department of Emergency Medicine, Feinberg School of Medicine, Northwestern University, Chicago IL
    • Corresponding Author InformationAddress for correspondence: Paula Tanabe, PhD, MPH, 417 S Jefferson, #408, Chicago IL, 60607; 312-926-6483, fax 312-926-6274
  • ,
  • Stephen D. Persell, MD, MPH

      Affiliations

    • Division of General Internal Medicine, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago IL
  • ,
  • James G. Adams, MD

      Affiliations

    • Department of Emergency Medicine, Feinberg School of Medicine, Northwestern University, Chicago IL
  • ,
  • Jennifer C. McCormick, BA

      Affiliations

    • Department of Emergency Medicine, Feinberg School of Medicine, Northwestern University, Chicago IL
  • ,
  • Zoran Martinovich, PhD

      Affiliations

    • Mental Health Services and Policy Program, Feinberg School of Medicine, Northwestern University, Chicago IL.
  • ,
  • David W. Baker, MD, MPH

      Affiliations

    • Division of General Internal Medicine, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago IL

Received 6 June 2007; received in revised form 11 September 2007; accepted 15 October 2007. published online 21 January 2008.

Study objective

We determine the proportion of patients with increased emergency department (ED) blood pressure and no history of hypertension who have persistently increased blood pressure at home, describe characteristics associated with sustained blood pressure increase, and examine the relationship between pain and anxiety and the change in blood pressure after ED discharge.

Methods

This was a prospective cohort study. Patients with no history of hypertension and 2 blood pressure measurements of at least 140/90 mm Hg who were treated in an urban ED were enrolled, provided with home blood pressure monitors, and asked to take their blood pressure twice a day for 1 week. Outcome measures were increased mean home blood pressure (140/90 mm Hg or greater), and correlations between ED anxiety (Spielberger State Anxiety Scale) or pain (10-point scale) and the change in blood pressure after discharge. Potential relevant predictors were recorded and a multivariate model was constructed to assess the relationship between these predictors and increased home blood pressure.

Results

189 patients were enrolled and 156 returned the monitors and completed the protocol. Increased mean home blood pressure was present in 79 of 156 (51%) patients and was associated with older age and being black. Of patients with ED blood pressures meeting criteria for stage I hypertension, 6% had home blood pressures meeting stage II hypertension, 36% stage I, and 52% prehypertension, and 6% had normal blood pressure For patients with ED blood pressures meeting stage II criteria, the corresponding percentages were 28%, 31%, 33%, and 8%, respectively. The difference between home and ED systolic blood pressures was not associated with anxiety (r=–.03; P=.69) and showed a slight association with pain in the opposite direction from what was expected (r=.18; P=.03).

Conclusion

Patients without diagnosed hypertension and increased ED blood pressures often have persistently increased home blood pressures, which does not appear to be related to pain or anxiety in the ED.

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 Supervising editors: Keith A. Marrill, MD; Donald M. Yealy, MDAuthor contributions: PT had full access to all of the data in the study and takes full responsibility for the integrity of the data and the accuracy of the analysis. PT, JGA, and DWB were responsible for study concept and design. PT and JCM acquired the data. PT, SDP, JGA, ZM, and DWB were responsible for analysis and interpretation of data. PT and SDP were responsible for drafting of the article. JGA, JCM, DWB, and ZM were responsible for critical revision of the article for important intellectual content. PT and ZM were responsible for statistical analysis. PT obtained funding. PT and SDP were responsible for study supervision. PT takes responsibility for the paper as a whole.Funding and support: This study was funded by the Agency for Healthcare Research and Quality, RO3 HSO15619-01A1. The agency had no role in the development of the study, review of data, or role in manuscript development. Dr. Tanabe was supported also supported in part by the Northwestern Memorial Hospital Excellence in Academic Medicine grant.Publication dates: Available online January 18, 2008.Reprints not available from authors.

PII: S0196-0644(07)01670-8

doi:10.1016/j.annemergmed.2007.10.017

Annals of Emergency Medicine
Volume 51, Issue 3 , Pages 221-229, March 2008