Annals of Emergency Medicine
Volume 51, Issue 6 , Pages 707-713 , June 2008

Is the Combination of Negative Computed Tomography Result and Negative Lumbar Puncture Result Sufficient to Rule Out Subarachnoid Hemorrhage?

  • Jeffrey J. Perry, MD, MSc

      Affiliations

    • Department of Emergency Medicine, University of Ottawa, Ottawa, Ontario, Canada
    • Corresponding Author InformationAddress for reprints: Jeffrey J. Perry, MD, MSc, Department of Emergency Medicine, University of Ottawa; 613-798-5555 ext 18763, fax 613-761-5351
    • ,
  • Alena Spacek, MD

      Affiliations

    • Department of Emergency Medicine, University of Ottawa, Ottawa, Ontario, Canada
    • ,
  • Melissa Forbes, MD

      Affiliations

    • Department of Family Medicine, University of Ottawa, Ottawa, Ontario, Canada
    • ,
  • George A. Wells, MSc, PhD

      Affiliations

    • Department of Epidemiology and Community Medicine, University of Ottawa, Ottawa, Ontario, Canada.
    • ,
  • Melodie Mortensen, BScRN, CNNC

      Affiliations

    • Department of Emergency Medicine, University of Ottawa, Ottawa, Ontario, Canada
    • ,
  • Cheryl Symington, RN, ENCC

      Affiliations

    • Department of Emergency Medicine, University of Ottawa, Ottawa, Ontario, Canada
    • ,
  • Nicole Fortin, RN

      Affiliations

    • Department of Emergency Medicine, University of Ottawa, Ottawa, Ontario, Canada
    • ,
  • Ian G. Stiell, MD, MSc

      Affiliations

    • Department of Emergency Medicine, University of Ottawa, Ottawa, Ontario, Canada

Received 20 June 2007 ,Revised 14 September 2007 ,Accepted 24 October 2007.

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 Supervising editor: Robert Silbergleit, MD

 Author contributions: JJP conceived the study, designed the trial, and obtained research funding. JJP and AS supervised the conduct of the trial and data collection. JJP, AS, MF, MM, CS, and NF undertook recruitment of participating centers and patients and managed the data, including quality control. IGS assisted with the design of the study and in preparing the manuscript. GAW and JJP provided statistical advice on study design and analyzed the data. JJP drafted the article, and all authors contributed substantially to its revision. JJP takes responsibility for the paper as a whole.

 Funding and support: By Annals policy, all authors are required to disclose any and all commercial, financial, and other relationships in any way related to the subject of this article, that might create any potential conflict of interest. The authors have stated that no such relationships exist. See the Manuscript Submission Agreement in this issue for examples of specific conflicts covered by this statement. Peer-reviewed funding was from the following sources: The Ontario Ministry of Health and Long Term Care, the physicians of Ontario through the Physician's Services Foundation, the Canadian Institutes for Health Research, and the Canadian Association of Emergency Physicians. Dr. Perry is a Career Scientist funded by the Ontario Ministry of Health, and Dr. Stiell holds a University Health Research Professor award from the University of Ottawa.

 Publication dates: Available online January 11, 2008.

PII: S0196-0644(07)01735-0

doi: 10.1016/j.annemergmed.2007.10.025

Annals of Emergency Medicine
Volume 51, Issue 6 , Pages 707-713 , June 2008

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