Annals of Emergency Medicine
Volume 51, Issue 3 , Pages 285-288 , March 2008

The Many Faces of MRSA: Community-Acquired Infection Knows No Bounds

  • Maryn McKenna (Special Contributor to Annals News & Perspective)

      Affiliations

    • Maryn McKenna is a Minneapolis journalist. Her book on MRSA will be published by Free Press in 2009.

References 

  1. Barber M. Staphylococcal infection due to penicillin-resistant strains. BMJ. 1947;863–865
  2. Jevons M. “Celbenin”-resistant staphylococci. BMJ. 1961;124–125
  3. Locksley RM, Cohen ML, Quinn TC, et al. Multiply antibiotic-resistant Staphylococcus aureus: introduction, transmission, and evolution of nosocomial infection. Ann Intern Med. 1982;97:317–324
  4. “Protecting 5 Million Lives”. http://www.ihi.org/NR/rdonlyres/A96E0639-A979-44F6-A0FF-20329E492F44/4230/5MillionLivespressreleaseupdatedDec26FINALFINAL.pdf2006;Accessed December 30, 2007
  5. Wisplinghoff H, Bischoff T, Tallent SM, et al. Nosocomial bloodstream infections in US hospitals: analysis of 24,179 cases from a prospective nationwide surveillance study. Clin Infect Dis. 2004;39:309–317
  6. Klevens RM, Edwards JR, Tenover FC, et al. Changes in the epidemiology of methicillin-resistant Staphylococcus aureus in intensive care units in US hospitals, 1992-2003. Clin Infect Dis. 2006;42:389–391
  7. Cosgrove SE, Qi Y, Kaye KS, et al. The impact of methicillin resistance in Staphylococcus aureus bacteremia on patient outcomes: mortality, length of stay, and hospital charges. Infect Control Hosp Epidemiol. 2005;26:166–174
  8. Herold BC, Immergluck LC, Maranan MC, et al. Community-acquired methicillin-resistant Staphylococcus aureus in children with no identified predisposing risk. JAMA. 1998;279:593–598
  9. Daum RS, Ito T, Hiramatsu K, et al. A novel methicillin-resistance cassette in community-acquired methicillin-resistant Staphylococcus aureus isolates of diverse genetic backgrounds. J Infect Dis. 2002;186:1344–1347
  10. Centers for Disease Control and Prevention. Four Pediatric Deaths from Community-Acquired Methicillin-Resistant Staphylococcus aureus—Minnesota and North Dakota, 1997–1999. MMWR. 1999;48:707–710
  11. Shahin R, Johnson IL, Jamieson F, et al. Methicillin-resistant Staphylococcus aureus carriage in a child care center following a case of disease (Toronto Child Care Center Study Group). Arch Pediatr Adolesc Med. 1999;153:864–868
  12. Lindenmayer JM, Schoenfeld S, O’Grady R, et al. Methicillin-resistant Staphylococcus aureus in a high school wrestling team and the surrounding community. Arch Intern Med. 1998;158:895–899
  13. Baggett HC, Hennessy TW, Rudolph K, et al. Community-onset methicillin-resistant Staphylococcus aureus associated with antibiotic use and the cytotoxin Panton-Valentine leukocidin during a furunculosis outbreak in rural Alaska. J Infect Dis. 2004;189:1565–1573
  14. Kazakova SV, Hageman JC, Matava M, et al. A clone of methicillin-resistant Staphylococcus aureus among professional football players. N Engl J Med. 2005;352:468–475
  15. Pan ES, Diep BA, Carleton HA, et al. Increasing prevalence of methicillin-resistant Staphylococcus aureus infection in California jails. Clin Infect Dis. 2003;37:1384–1388
  16. Lee NE, Taylor MM, Bancroft E, et al. Risk factors for community-associated methicillin-resistant Staphylococcus aureus skin infections among HIV-positive men who have sex with men. Clin Infect Dis. 2005;40:1529–1534
  17. Mongkolrattanothai K, Boyle S, Kahana MD, et al. Severe Staphylococcus aureus infections caused by clonally related community-acquired methicillin-susceptible and methicillin-resistant isolates. Clin Infect Dis. 2003;37:1050–1058
  18. Miller LG, Perdreau-Remington F, Rieg G, et al. Necrotizing fasciitis caused by community-associated methicillin-resistant Staphylococcus aureus in Los Angeles. N Engl J Med. 2005;352:1445–1453
  19. Gonzalez BE, Teruya J, Mahoney DH, et al. Venous thrombosis associated with staphylococcal osteomyelitis in children. Pediatrics. 2006;117:1673–1679
  20. Adem PV, Montgomery CP, Husain AN, et al. Staphylococcus aureus sepsis and the Waterhouse-Friderichsen syndrome in children. N Engl J Med. 2005;353:1245–1251
  21. Gillet Y, Vanhems P, Lina G, et al. Factors predicting mortality in necrotizing community-acquired pneumonia caused by Staphylococcus aureus containing Panton-Valentine leukocidin. Clin Infect Dis. 2007;45:315–321
  22. Centers for Disease Control and Prevention. Public Health Dispatch: Outbreaks of Community-Associated Methicillin-Resistant Staphylococcus aureus Skin Infections—Los Angeles County, California, 2002-2003. MMWR. 2003;52:88
  23. Moran GJ, Amii RN, Abrahamian FM, et al. Methicillin-resistant Staphylococcus aureus in community-acquired skin infections. Emerg Infect Dis. 2005;11:928–930
  24. Frazee BW, Lynn J, Charlebois ED, et al. High prevalence of methicillin-resistant Staphylococcus aureus in emergency department skin and soft tissue infections. Ann Emerg Med. 2005;45:311–320
  25. Moran GJ, Talan DA. Community-associated methicillin-resistant Staphylococcus aureus: is it in your community and should it change practice?. Ann Emerg Med. 2005;45:321–322
  26. Fridkin SK, Hageman JC, Morrison M, et al. Methicillin-resistant Staphylococcus aureus disease in three communities. N Engl J Med. 2005;352:1436–1444
  27. King MD, Humphrey BJ, Wang YF, et al. Emergence of community-acquired methicillin-resistant Staphylococcus aureus USA 300 clone as the predominant cause of skin and soft-tissue infections. Ann Intern Med. 2006;144:309–317
  28. Moran GJ, Krishnadasan A, Gorwitz RJ, et al. Methicillin-resistant S. aureus infections among patients in the emergency department. N Engl J Med. 2006;355:666–674
  29. Strategies for Clinical Management of MRSA in the Community: Summary of an Experts’ Meeting Convened by the Centers for Disease Control and Prevention. http://cdc.gov/ncidod/dhqp/pdf/ar/CAMRSA_ExpMtgStrategies.pdf2006;Accessed December 31, 2007
  30. Brady JM, Stemper ME, Weigel A, et al. Sporadic “transitional” community-associated methicillin-resistant Staphylococcus aureus strains from health care facilities in the United States. J Clin Microbiol. 2007;45:2654–2661
  31. Moore ZS, Jerris RC, Hilinski JA. High prevalence of inducible clindamycin resistance among Staphylococcus aureus isolates from patients with cystic fibrosis. J Cyst Fibros. 2007;
  32. Moriarity R. Trimethoprim-sulfamethoxazole resistance in community-acquired methicillin resistant staphylococcus aureus. Ann Emerg Med. 2007;50:S57
  33. Miller LG, Perdreau-Remington F, Bayer AS, et al. Clinical and epidemiologic characteristics cannot distinguish community-associated methicillin-resistant Staphylococcus aureus infection from methicillin-susceptible S. aureus infection: a prospective investigation. Clin Infect Dis. 2007;44:471–482
  34. Meengs MR, Giles BK, Chisholm CD, et al. Hand washing frequency in an emergency department. Ann Emerg Med. 1994;23:1307–1312
  35. Dorsey ST, Cydulka RK, Emerman CL. Is handwashing teachable?: failure to improve handwashing behavior in an urban emergency department. Acad Emerg Med. 1996;3:360–365
  36. Larson EL, Albrecht S, O’Keefe M. Hand hygiene behavior in a pediatric emergency department and a pediatric intensive care unit: comparison of use of 2 dispenser systems. Am J Crit Care. 2005;14:304–1311quiz 12
  37. Huang R, Mehta S, Weed D, et al. Methicillin-resistant Staphylococcus aureus survival on hospital fomites. Infect Control Hosp Epidemiol. 2006;27:1267–1269
  38. Jacobsen S. Seeking cure to staph’s mystery: After firefighter dies, his wife asks: How could this happen?. Dallas Morning News. 2007;November 18
  39. Tucker A. Spread of Rare Infection Sparks Concern. 2007;WTEN-TV Aug. 30
  40. Storch J, Jacoby JL, Heller M. Community-associated methicillin resistant Staphylococcus aureus in an emergency medicine resident: lessons learned. Ann Emerg Med. 2005;46:384–385

 Funding and support: By Annals policy, all authors are required to disclose any and all commercial, financial, and other relationships in any way related to the subject of this article, that might create any potential conflict of interest. The author has stated that no such relationships exist. See the Manuscript Submission Agreement in this issue for examples of specific conflicts covered by this statement.

PII: S0196-0644(08)00351-X

doi: 10.1016/j.annemergmed.2008.01.320

Annals of Emergency Medicine
Volume 51, Issue 3 , Pages 285-288 , March 2008