Annals of Emergency Medicine
Volume 53, Issue 2 , Pages 189-197 , February 2009

Cost-Consequence Analysis Comparing 2-Octyl Cyanoacrylate Tissue Adhesive and Suture for Closure of Simple Lacerations: A Randomized Controlled Trial

  • S.Y. Man, FRCSEd

      Affiliations

    • Accident and Emergency Medicine Academic Unit, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China
    • ,
  • E.M.L. Wong, MSN

      Affiliations

    • Department of Nursing Studies, the Chinese University of Hong Kong, Hong Kong, China
    • ,
  • Y.C. Ng, PhD

      Affiliations

    • Department of Economics, Hong Kong Baptist University, Hong Kong, China
    • ,
  • P.F. Lau, MA

      Affiliations

    • Accident and Emergency Department, Pamela Youde Nethersole Eastern Hospital, Hong Kong, China
    • ,
  • M.S. Chan, MS

      Affiliations

    • Accident and Emergency Medicine Academic Unit, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China
    • ,
  • V. Lopez, PhD

      Affiliations

    • School of Nursing (New South Wales and Australia Capital Territories), Australian Catholic University, Australia
    • ,
  • P.S.K. Mak, BSN

      Affiliations

    • Accident and Emergency Medicine Academic Unit, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China
    • ,
  • C.A. Graham, MD

      Affiliations

    • Accident and Emergency Medicine Academic Unit, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China
    • ,
  • T.H. Rainer, MD

      Affiliations

    • Accident and Emergency Medicine Academic Unit, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China
    • Corresponding Author InformationAddress for reprints: T. H. Rainer, Accident and Emergency Medicine Academic Unit, Chinese University of Hong Kong, Trauma and Emergency Centre, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR; 852-2632-1033, fax: 852-2648-1469

Received 25 July 2007 ,Revised 19 February 2008 ,Accepted 3 March 2008.

References 

  1. DeBoard RH, Rondeau DF, Kang CS, et al. Principles of basic wound evaluation and management in the emergency department. Emerg Med Clin North Am. 2007;25:23–39
  2. Singer AJ, Quinn JV, Clark RE, et al. TraumaSeal Study Group Closure of lacerations and incisions with octylcyanoacrylate: a multicenter randomized controlled trial. Surgery. 2002;131:270–276
  3. Farion KJ, Osmond MH, Hartling L, et al. Tissue adhesives for traumatic lacerations in children and adults. Cochrane Database Syst Rev. 2002;3:CD003326.
  4. Hong Kong Hospital Authority Intranet. Statistic and research section home site. http://shis.home/shis/home/default.htmAccessed March 7, 2006.
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  6. Quinn JV, Drzewiecki AE, Stiell IG, et al. Appearance scales to measure cosmetic outcomes of healed lacerations. Am J Emerg Med. 1995;13:229–231
  7. Quinn JV, Wells GA. An assessment of clinical evaluation scales. Acad Emerg Med. 1998;5:583–586
  8. Hollander JE, Singer AJ, Valentine S, et al. Wound registry: development and validation. Ann Emerg Med. 1995;25:675–678
  9. Huskisson EC. Measurement of pain. Lancet. 1974;2:1127–1131
  10. Todd KH, Funk JP. The minimum clinically important difference in physician-assigned visual analog pain score. Acad Emerg Med. 1996;3:142–146
  11. Todd KH, Funk KG, Funk JP, et al. Clinical significance of reported changes in pain severity. Ann Emerg Med. 1996;27:485–489
  12. Torgerson D, Raftery J. Economics notes: measuring outcomes in economic evaluations. BMJ. 1999;318:1413
  13. Coulthard P, Worthington H, Esposito M, et al. Tissue adhesives for closure of surgical incisions. Cochrane Database Syst Rev. 2004;2:CD004287.

 Supervising editor: Judd E. Hollander, MD

 Author contributions: THR has overseen the entire planning, execution, and analysis of the study. EMLW conceived the study and obtained approval and the grant for the study. PFL and MSC participated in staff training in the tissue adhesive application. SYM, CAG, and THR prepared the statistical analysis and were assisted by EMLW, YCN, and PSKM. EMLW and PSKM participated in data collection for the study. YCN and VL were involved in the grant proposal for the study. SYM wrote the first draft of the article and prepared the article, and all authors have contributed to the final version. THR takes responsibility for the paper as a whole.

 Funding and support: By Annals policy, all authors are required to disclose any and all commercial, financial, and other relationships in any way related to the subject of this article, that might create any potential conflict of interest. See the Manuscript Submission Agreement in this issue for examples of specific conflicts covered by this statement. This study was supported by the Health and Health Services Research Fund (project code 03040071). No financial support was received from any commercial source to conduct this study. Competing interests: None declared.

 Publication dates: Available online April 28, 2008.

PII: S0196-0644(08)00568-4

doi: 10.1016/j.annemergmed.2008.03.003

Annals of Emergency Medicine
Volume 53, Issue 2 , Pages 189-197 , February 2009

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