Annals of Emergency Medicine
Volume 53, Issue 4 , Pages 439-450.e10 , April 2009

Adverse Drug Events Associated With the Antidotes for Methanol and Ethylene Glycol Poisoning: A Comparison of Ethanol and Fomepizole

Presented at the North American Congress of Clinical Toxicology, October 2007, New Orleans, LA.

  • Katherine J. Lepik, BSc(Pharm), MSc

      Affiliations

    • British Columbia Drug and Poison Information Centre, Vancouver, British Columbia, Canada
    • Corresponding Author InformationAddress for correspondence: Katherine J. Lepik, BSc(Pharm), MSc, British Columbia Drug and Poison Information Centre, 1081 Burrard Street, Vancouver, BC, Canada V6Z 1Y6; 604-682-5050, fax 604-806-8262
  • ,
  • Adrian R. Levy, PhD

      Affiliations

    • University of British Columbia, School of Population and Public Health, Vancouver, British Columbia, Canada
    • Centre for Health Evaluation and Outcome Sciences at St. Paul's Hospital, Vancouver, British Columbia, Canada
  • ,
  • Boris G. Sobolev, PhD

      Affiliations

    • University of British Columbia, School of Population and Public Health, Vancouver, British Columbia, Canada
    • Centre for Clinical Epidemiology and Evaluation at Vancouver General Hospital, Vancouver, British Columbia, Canada
  • ,
  • Roy A. Purssell, MD

      Affiliations

    • British Columbia Drug and Poison Information Centre, Vancouver, British Columbia, Canada
    • Vancouver General Hospital, Department of Emergency Medicine, Vancouver, British Columbia, Canada
  • ,
  • Christopher R. DeWitt, MD

      Affiliations

    • British Columbia Drug and Poison Information Centre, Vancouver, British Columbia, Canada
    • St. Paul's Hospital, Department of Emergency Medicine, Vancouver, British Columbia, Canada
  • ,
  • Gunnar D. Erhardt, MD

      Affiliations

    • British Columbia Drug and Poison Information Centre, Vancouver, British Columbia, Canada
    • Royal Columbian Hospital, Department of Emergency Medicine, New Westminster, British Columbia, Canada
  • ,
  • James R. Kennedy, MD

      Affiliations

    • British Columbia Drug and Poison Information Centre, Vancouver, British Columbia, Canada
    • Department of Internal Medicine, Vancouver, British Columbia, Canada
  • ,
  • Derek E. Daws, BSc(Pharm)

      Affiliations

    • British Columbia Drug and Poison Information Centre, Vancouver, British Columbia, Canada
  • ,
  • Jane L. Brignall, MD

      Affiliations

    • British Columbia Drug and Poison Information Centre, Vancouver, British Columbia, Canada

Received 22 September 2007 ,Revised 28 April 2008 ,Accepted 5 May 2008.

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 Supervising editor: E. Martin Caravati, MD, MPH

 Author contributions: KJL, ARL, BGS, RAP, and DED conceived and designed the study. KJL and JLB performed data collection. RAP, CRD, GDE, and JRK acted as expert reviewers. BGS was the senior statistician. KJL analyzed the data. KJL drafted the article, and all authors contributed substantially to its revision. KJL takes responsibility for the paper as a whole.

 Funding and support: By Annals policy, all authors are required to disclose any and all commercial, financial, and other relationships in any way related to the subject of this article, that might create any potential conflict of interest. See the Manuscript Submission Agreement in this issue for examples of specific conflicts covered by this statement. KJL was supported by a training fellowship from the Michael Smith Foundation for Health Research (MSFHR). ARL is supported by MSFHR Senior Scholar and Canadian Institutes of Health Research New Investigator awards. BGS was supported by the Canada Research Chair Program.

 Publication dates: Available online July 18, 2008.

 Earn CME Credit: Continuing Medical Education is available for this article at: www.ACEP-EMedHome.com.

 Reprints not available from the authors.

PII: S0196-0644(08)00796-8

doi: 10.1016/j.annemergmed.2008.05.008

Annals of Emergency Medicine
Volume 53, Issue 4 , Pages 439-450.e10 , April 2009