Annals of Emergency Medicine
Volume 52, Issue 6 , Pages 705-713 , December 2008

The Relative Efficacy of Meperidine for the Treatment of Acute Migraine: A Meta-analysis of Randomized Controlled Trials

Presented at the Society for Academic Emergency Medicine National Meeting, May 2008, Washington, DC.

  • Benjamin W. Friedman, MD, MSc

      Affiliations

    • Department of Emergency Medicine, Albert Einstein College of Medicine, Bronx, NY
    • Corresponding Author InformationAddress for reprints: Benjamin W. Friedman, MD, MSc, Department of Emergency Medicine, Albert Einstein College of Medicine, Montefiore Medical Center, 111 East 210th Street, Bronx, NY 10467; 718-920-6626, fax 718-798-0730
    • ,
  • Alok Kapoor, MD, MSc

      Affiliations

    • Hospital Medicine Unit, Section of General Internal Medicine, Boston University, Boston, MA
    • ,
  • Matt S. Friedman, MD

      Affiliations

    • Department of Emergency Medicine, Mount Sinai Medical Center, New York, NY
    • ,
  • Michael L. Hochberg, MD

      Affiliations

    • Department of Emergency Medicine, Albert Einstein College of Medicine, Bronx, NY
    • ,
  • Brian H. Rowe, MD, MSc

      Affiliations

    • Department of Emergency Medicine and Department of Public Health Sciences, School of Public Health, University of Alberta, Edmonton, Alberta, Canada

Received 18 March 2008 ,Revised 7 May 2008 ,Accepted 20 May 2008.

References 

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  23. Ospina MB, Kelly K, Klassen TP, et al. Publication bias of randomized controlled trials in emergency medicine. Acad Emerg Med. 2006;13:102–108
  24. Birnbaum A, Esses D, Bijur PE, et al. Randomized double-blind placebo-controlled trial of two intravenous morphine dosages (0.10 mg/kg and 0.15 mg/kg) in emergency department patients with moderate to severe acute pain. Ann Emerg Med. 2007;49:445–453453.e1-2
  25. Chang AK, Bijur PE, Meyer RH, et al. Safety and efficacy of hydromorphone as an analgesic alternative to morphine in acute pain: a randomized clinical trial. Ann Emerg Med. 2006;48:164–172
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  28. Friedman BW, Corbo J, Lipton RB, et al. A trial of metoclopramide vs sumatriptan for the emergency department treatment of migraines. Neurology. 2005;64:463–468
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 Supervising editors: Michael D. Brown, MD, MSc; Peter C. Wyer, MD

 Author contributions: BWF and BHR identified the question of interest. AK and BWF designed the search strategy. BWF reviewed all relevant citations. BWF, MSF, and MLH abstracted data. BWF and AK reviewed and analyzed abstracted data. BWF, AK, and BHR interpreted and contextualized the results. BWF and AK drafted the article; all authors contributed substantially to editing and revision of the manuscript. BWF takes responsibility for the paper as a whole.

 Funding and support: By Annals policy, all authors are required to disclose any and all commercial, financial, and other relationships in any way related to the subject of this article, that might create any potential conflict of interest. See the Manuscript Submission Agreement in this issue for examples of specific conflicts covered by this statement. Dr. Friedman is supported by a career development award (K23NS051049) from the National Institute of Neurological Disorders and Stroke. Dr. Rowe is supported by a 21st Century Research Chair Award from the government of Canada (Ottawa, Ontario).

 Publication dates: Available online July 16, 2008.

PII: S0196-0644(08)00906-2

doi: 10.1016/j.annemergmed.2008.05.036

Annals of Emergency Medicine
Volume 52, Issue 6 , Pages 705-713 , December 2008

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