Annals of Emergency Medicine
Volume 53, Issue 4 , Pages 451-453 , April 2009

Ethanol: Tastes Great! Fomepizole: Less Filling!

  • Marco L.A. Sivilotti, MD, MSc

      Affiliations

    • Corresponding Author InformationAddress for correspondence: Marco L. A. Sivilotti, MD, MSc, Department of Emergency Medicine, Queen's University, 76 Stuart Street, Kingston, ON, Canada, K7L 2V7; 613-548-2368, fax 613-548-1374

References 

  1. Barceloux DG, Krenzelok EP, Olson K, et al. American Academy of Clinical Toxicology practice guidelines on the treatment of ethylene glycol poisoning (Ad Hoc Committee). J Toxicol Clin Toxicol. 1999;37:537–560
  2. Barceloux DG, Bond GR, Krenzelok EP, et al. American Academy of Clinical Toxicology Ad Hoc Committee on the Treatment Guidelines for Methanol Poisoning (American Academy of Clinical Toxicology practice guidelines on the treatment of methanol poisoning). J Toxicol Clin Toxicol. 2002;40:415–446
  3. Hantson P, Wittebole X, Haufroid V. Ethanol therapy for methanol poisoning: duration and problems. Eur J Emerg Med. 2002;9:278–279
  4. Cobaugh DJ, Gibbs M, Shapiro DE, et al. A comparison of the bioavailabilities of oral and intravenous ethanol in healthy male volunteers. Acad Emerg Med. 1999;6:984–988
  5. Berberet BR, Burda AM, Lodolce AE. Unavailability of 10% alcohol in 5% dextrose injection. Am J Health Syst Pharm. 2005;62:2344–2345
  6. Borron SW, Caravati EM, Cobaugh DJ, et al. Antidote Summit Authorship Group Expert consensus guidelines for stocking of antidotes in hospitals that provide emergency care. Ann Emerg Med. 2009;In press.
  7. Lepik KJ, Levy AR, Sobolev BG, et al. Adverse drug events associated with the antidotes for methanol and ethylene glycol poisoning: a comparison of ethanol and fomepizole. Ann Emerg Med. 2009;53:439–450
  8. Agbabiaka TB, Savovic J, Ernst E. Methods for causality assessment of adverse drug reactions: a systematic review. Drug Saf. 2008;31:21–37
  9. Paasma R, Hovda KE, Tikkerberi A, et al. Methanol mass poisoning in Estonia: outbreak in 154 patients. Clin Toxicol. 2007;45:152–157
  10. Caravati EM, Heileson HL, Jones M. Treatment of severe pediatric ethylene glycol intoxication without hemodialysis. J Toxicol Clin Toxicol. 2004;42:255–259
  11. Innes G, Grafstein E, McGrogan J. Do emergency physicians know the costs of medical care?. CJEM. 2000;2:95–102
  12. Bailey B, Bussieres JF. The cost of maintaining adequate antidote supplies. CMAJ. 2001;165:1467
  13. Sivilotti MLA, Eisen JS, Lee JS, et al. Can emergency departments not afford to carry essential antidotes?. CJEM. 2002;4:23–33
  14. Gorman SK, Zed PJ, Purssell RA, et al. Antidote stocking in British Columbia hospitals. CJEM. 2003;5:12–17
  15. Juurlink DN, McGuigan MA, Paton TW, et al. Availability of antidotes at acute care hospitals in Ontario. CMAJ. 2001;165:27–30
  16. American Association of Poison Control Centers. American Association of Poison Control Centers' National Poison Data System annual report data. http://www.aapcc.orgAccessed June 19, 2008

 Supervising editor: E. Martin Caravati, MD, MPH

 Funding and support: By Annals policy, all authors are required to disclose any and all commercial, financial, and other relationships in any way related to the subject of this article that might create any potential conflict of interest. The author has stated that no such relationships exist. See the Manuscript Submission Agreement in this issue for examples of specific conflicts covered by this statement.

 Publication date: Available online November 4, 2008.

 Earn CME Credit: Continuing Medical Education is available for this article at: www.ACEP-EMedHome.com.

 Reprints not available from author.

PII: S0196-0644(08)01568-0

doi: 10.1016/j.annemergmed.2008.07.038

Annals of Emergency Medicine
Volume 53, Issue 4 , Pages 451-453 , April 2009

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