Annals of Emergency Medicine
Volume 54, Issue 2 , Pages 147-152 , August 2009

Risk of Thromboembolism Varies, Depending on Category of Immobility in Outpatients

  • Daren M. Beam, MS

      Affiliations

    • Brody School of Medicine at East Carolina University, Greenville, NC
    • ,
  • D. Mark Courtney, MD

      Affiliations

    • Northwestern Memorial Hospital, Chicago, IL
    • ,
  • Christopher Kabrhel, MD

      Affiliations

    • Massachusetts General Hospital, Boston, MA
    • ,
  • Christopher L. Moore, MD

      Affiliations

    • Yale University School of Medicine, New Haven, CT
    • ,
  • Peter B. Richman, MD

      Affiliations

    • Mayo Clinic, Scottsdale, AZ
    • ,
  • Jeffrey A. Kline, MD

      Affiliations

    • Carolinas Medical Center, Charlotte, NC
    • Corresponding Author InformationAddress for reprints: Jeffrey A. Kline, MD, Emergency Medicine Research, Department of Emergency Medicine, Carolinas Medical Center, PO Box 32861, Charlotte, NC 28323-2861; 704-355-7092, fax 704-355-7047

Received 14 July 2008 ,Revised 15 October 2008 ,Accepted 31 October 2008.

References 

  1. Dalen JE. Pulmonary embolism: what have we learned since Virchow? (Natural history, pathophysiology, and diagnosis). Chest. 2002;122:1440–1456
  2. Wells PS, Anderson DR, Rodger M, et al. Derivation of a simple clinical model to categorize patients' probability of pulmonary embolism: increasing the models utility with the SimpliRED D-dimer. Thromb Haemost. 2000;83:416–420
  3. Kline JA, Courtney DM, Kabrhel C, et al. Prospective multicenter evaluation of the pulmonary embolism rule-out criteria. J Thromb Haemost. 2008;6:772–780
  4. Runyon MS, Webb WB, Jones AE, et al. Comparison of the unstructured clinician estimate of low clinical probability for pulmonary embolism to the Canadian Score or the Charlotte Rule. Acad Emerg Med. 2005;12:587–593
  5. Kline JA, Johnson CL, Webb WB, et al. Prospective study of clinician-entered research data in the emergency department using an internet-based system after the HIPAA Privacy Rule. BMC Med Inform Decis Mak. 2005;4:17–25
  6. Kline JA, Mitchell AM, Runyon MS, et al. Electronic medical record review as a surrogate to telephone follow-up to establish outcome for diagnostic research studies in the emergency department. Acad Emerg Med. 2005;12:1127–1232
  7. Philbrick JT, Shumate R, Siadaty MS, et al. Air travel and venous thromboembolism: a systematic review. J Gen Intern Med. 2007;22:107–114
  8. Hodkinson PD, Hunt BJ, Ernsting J. Is mild normobaric hypoxia a risk factor for venous thromboembolism?. J. Thromb Haemost. 2003;10:2131–2133
  9. Toff WD, Jones RD, Ford I, et al. Effect of hypobaric hypoxia, simulating conditions during long-haul air travel, on coagulation, fibrinolysis, platelet function, and endothelial activation. JAMA. 2006;295:2251–2261

 Provide feedback on this article at the journal's Web site, www.annemergmed.com.

 Supervising editor: David L. Schriger, MD, MPH

 Author contributions: DMB collected and analyzed data and wrote the first draft of the article. DMC performed the statistical and graphic analyses and edited the article. CK, CLM, and PBR helped develop this idea, participated in study definitions, performed data entry, and assisted with article production. CK, CLM, PBR, and JAK enrolled patients and performed database queries. JAK conceived the work, obtained funding, contributed to the primary analyses, and edited the article. JAK takes responsibility for the paper as a whole.

 Funding and support: By Annals policy, all authors are required to disclose any and all commercial, financial, and other relationships in any way related to the subject of this article that might create any potential conflict of interest. See the Manuscript Submission Agreement in this issue for examples of specific conflicts covered by this statement. Supported by a Resident Research Award from the Emergency Medicine Foundation.

 Publication date: Available online January 7, 2009.

PII: S0196-0644(08)01975-6

doi: 10.1016/j.annemergmed.2008.10.033

Annals of Emergency Medicine
Volume 54, Issue 2 , Pages 147-152 , August 2009

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