Annals of Emergency Medicine
Volume 54, Issue 3 , Pages 432-439.e2 , September 2009

Tamsulosin for Ureteral Stones in the Emergency Department: A Randomized, Controlled Trial

Presented at the 2007 American College of Emergency Physicians Research Forum, October 2007, Seattle, WA.

  • Robinson M. Ferre, MD, Capt, USAF, MC

      Affiliations

    • Wilford Hall Medical Center, 59th Medical Wing, Lackland Air Force Base, San Antonio, TX
    • ,
  • Jessica N. Wasielewski, MD

      Affiliations

    • Maine Medical Center, Department of Emergency Medicine, Portland, ME
    • ,
  • Tania D. Strout, RN, BSN, MS

      Affiliations

    • Maine Medical Center, Department of Emergency Medicine, Portland, ME
    • Corresponding Author InformationAddress for correspondence: Tania D. Strout, RN, BSN, MS, Maine Medical Center, Department of Emergency Medicine, 22 Bramhall Street, Portland, ME 04102; 207-662-7049, fax 207-662-7054
    • ,
  • Andrew D. Perron, MD, FACSM

      Affiliations

    • Maine Medical Center, Department of Emergency Medicine, Portland, ME

Received 9 June 2008 ,Revised 26 November 2008 ,Accepted 19 December 2008.

References 

  1. Pearle MS, Calhoun EA, Curhan GC, et al. Urologic Diseases in American Project: urolithiasis. J Urol. 2005;173:848–857
  2. Stamatelou KK, Francis ME, Jones CA, et al. Time trends in reported prevalence of kidney stones in the United States: 1976-1994. Kidney Int. 2003;63:1817–1823
  3. Litwin MS, Saigal CS, Yano EM, et al. Urologic Diseases in American Project: analytical methods and principal findings. J Urol. 2005;173:933–937
  4. Sheafor DH, Hertxberg BS, Freed KS, et al. Nonenhanced helical CT and US in the emergency evaluation of patients with renal colic: prospective comparison. Radiology. 2000;217:792–797
  5. Cervenakov I, Fillo J, Mardiak J, et al. Speedy elimination of ureterolithiasis in lower part of ureters with the alpha 1-blocker—tamsulosin. Int Urol Nephrol. 2002;34:25–29
  6. Dellabella M, Milanese G, Muzzonigro G. Efficacy of tamsulosin in the medical management of juxtavesical ureteral stones. J Urol. 2003;170:2202–2205
  7. Kupeli B, Irkilata L, Gurocak S, et al. Does tamsulosin enhance lower ureteral stone clearance with or without shock wave lithotripsy?. Urology. 2004;64:1111–1115
  8. Porpiglia F, Ghignone G, Fiori C, et al. Nifedipine versus tamsulosin for the management of lower ureteral stones. J Urol. 2004;172:568–571
  9. Autorino R, DeSio M, Damiano R, et al. The use of tamsulosin in the medical treatment of ureteral calculi: where do we stand?. Urol Res. 2005;33:460–464
  10. Dellabella M, Milanese G, Muzzonigro G. Randomized trial of the efficacy of tamsulosin, nifedipine and phloroglucinol in medical expulsive therapy for distal ureteral calculi. J Urol. 2005;174:167–172
  11. Yilmaz E, Batislam E, Basar MM, et al. The comparison and efficacy of 3 different α1-adrenergic blockers for distal ureteral stones. J Urol. 2005;173:2010–2012
  12. DeSio M, Autorino R, Di Lorenzo G, et al. Medical expulsive treatment of distal ureteral stones using tamsulosin: a single center experience. J Endourol. 2006;20:12–16
  13. Resim S, Ekerbicer H, Ciftci A. Effect of tamsulosin on the number and intensity of ureteral colic in patients with lower ureteral calculus. Int J Urol. 2005;12:615–620
  14. Resim S, Eckerbicer HC, Ciftci A. Role of tamsulosin in treatment of patients with steinstrasse developing after extracorporeal shock wave lithotripsy. Urology. 2005;66:945–948
  15. Dellabella M, Milanese G, Muzzonigro G. Medical-expulsive therapy for distal ureterolithiasis: randomized prospective study on role of corticosteroids used in combination with tamsulosin-simplified treatment regimen and health-related quality of life. Urology. 2005;66:712–715
  16. Singh A, Harrison J, Littlepage A. A systematic review of medical therapy to facilitate passage of ureteral calculi. Ann Emerg Med. 2007;50:552–563
  17. Hollingsworth JM, Rogers MA, Kaufman SR, et al. Medical therapy to facilitate urinary stone passage: a meta-analysis. Lancet. 2006;368:1171–1179
  18. Obara K, Takeda M, Shimura H, et al. Alpha-1 adrenoreceptor subtypes in the human ureter (characterization by RT-PCR and in situ hybridization). J Urol. 1996;155:47A
  19. Morita T, Wada I, Saeki H, et al. Ureteral urine transport: changes in bolus volume, peristaltic frequency, intraluminal pressure, and volume of flow resulting from autonomic drugs. J Urol. 1987;137:132–135
  20. Sigala S, Dellabella M, Milanese G, et al. Alpha-1 adrenoreceptor subtypes in male juxtavesical ureters: molecular and pharmacological characterization. Eur Urol. 2004;3:119
  21. Strout TD, Kendrick DB. Patient assessment: pain scales and observation in clinical practice. In:  Burton JH,  Miner JR editor. Emergency Sedation and Pain Management. Cambridge, UK: Cambridge University Press; 2008;p. 55–66
  22. Bushinsky DA, Coe FL, Moe OW. Nephrolithiasis. In:  Brenner BM,  Levine SA editor. Brenner and Rector's The Kidney. 8th ed.. Philadelphia, PA: Saunders; 2008;p. 1299–1308
  23. Ege G, Akman H, Kuzucu K, et al. Can computed tomography scout radiography replace plain film in the evaluation of patients with acute urinary tract colic?. Acta Radiol. 2004;45:469–473
  24. Dalrymple NC, Verga M, Anderson KR, et al. The value of unenhanced helical computerized tomography in the management of acute flank pain. J Urol. 1998;159:735–740

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 Supervising editor: Allan B. Wolfson, MD

 Author contributions: RMF, TDS, and ADP conceived the study and designed the trial. JNW and TDS acquired the data. RMF and TDS analyzed the data and interpreted the results. RMF and TDS drafted the article, whereas all authors revised it for intellectual content. TDS provided statistical expertise. All authors take responsibility for the paper as a whole.

 Funding and support: By Annals policy, all authors are required to disclose any and all commercial, financial, and other relationships in any way related to the subject of this article that might create any potential conflict of interest. See the Manuscript Submission Agreement in this issue for examples of specific conflicts covered by this statement. This study was funded by an academic grant from the Maine Medical Center Mentored Research Committee.

 Reprints not available from authors.

 Publication date: Available online February 5, 2009.

PII: S0196-0644(08)02183-5

doi: 10.1016/j.annemergmed.2008.12.026

Annals of Emergency Medicine
Volume 54, Issue 3 , Pages 432-439.e2 , September 2009

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