Annals of Emergency Medicine
Volume 53, Issue 6 , Pages 804-810 , June 2009

Hemostatic Efficacy of Modified Amylopectin Powder in a Lethal Porcine Model of Extremity Arterial Injury

  • Michael Kilbourne, MD

      Affiliations

    • Department of Surgery, Division of Clinical and Outcomes Research, R. Adams Cowley Shock Trauma Center, Baltimore, MD
    • Corresponding Author InformationAddress for correspondence: Michael Kilbourne, MD, R. Adams Cowley Shock Trauma Center, 22 South Greene St T1R60, Baltimore, MD 21201; 410-328-5377, fax 410-328-7175
    • ,
  • Kaspar Keledjian, MD

      Affiliations

    • Department of Surgery, Division of Clinical and Outcomes Research, R. Adams Cowley Shock Trauma Center, Baltimore, MD
    • ,
  • John R. Hess, MD, MPH

      Affiliations

    • Department of Pathology, University of Maryland School of Medicine, Baltimore, MD
    • ,
  • Thomas Scalea, MD

      Affiliations

    • Department of Surgery, Division of Clinical and Outcomes Research, R. Adams Cowley Shock Trauma Center, Baltimore, MD
    • ,
  • Grant V. Bochicchio, MD, MPH

      Affiliations

    • Department of Surgery, Division of Clinical and Outcomes Research, R. Adams Cowley Shock Trauma Center, Baltimore, MD

Received 3 July 2008 ,Revised 21 November 2008 ,Accepted 9 December 2008.

References 

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  10. Schreiber MA. The effect of recombinant factor VIIa on noncoagulopathic pigs with grade V liver injuries. J Am Coll Surg. 2003;196:691–697
  11. Sondeen JL, Coppes VG, Holcomb JB. Blood pressure at which rebleeding occurs after resuscitation in swine with aortic injury. J Trauma. 2003;54:S110–S117
  12. Holcomb JB. Fluid resuscitation in modern combat casualty care: lessons learned from Somalia. J Trauma. 2004;57:S46–S51

 Provide feedback on this article at the journal's Web site, www.annemergmed.com.

 Supervising editor: Stephen R. Thom, MD, PhD

 Author contributions: MK, JRH, and GVB conceived the study. TS and GVB obtained research funding. MK, KK, and GVB conducted all surgical procedures and data collection. MK and KK managed and analyzed the data. GVB provided statistical advice on the study design and data collection and reviewed all analyzed data. MK drafted the article. TS and GVB critically revised the article. MK takes responsibility for the paper as a whole.

 Funding and support: By Annals policy, all authors are required to disclose any and all commercial, financial, and other relationships in any way related to the subject of this article, that might create any potential conflict of interest. See the Manuscript Submission Agreement in this issue for examples of specific conflicts covered by this statement. Partial funding for this study was contributed by Hemostasis, LLC, St. Paul, MN.

 Publication date: Available online March 25, 2009.

 Reprints not available from the authors.

PII: S0196-0644(09)00007-9

doi: 10.1016/j.annemergmed.2008.12.041

Annals of Emergency Medicine
Volume 53, Issue 6 , Pages 804-810 , June 2009

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