Annals of Emergency Medicine
Volume 54, Issue 2 , Pages 301-307 , August 2009

Clevidipine, an Intravenous Dihydropyridine Calcium Channel Blocker, Is Safe and Effective for Treatment of Patients With Acute Severe Hypertension: Answers to the March 2009 Journal Club Questions

References 

  1. Pollack CV, Varon J, Garrison NA, et al. Clevidipine, an intravenous dihydropyridine calcium channel blocker, is safe and effective for the treatment of patients with acute severe hypertension. Ann Emerg Med. 2009;53:329–338
  2. Barrett TW, Schriger DL Annals of Emergency Medicine Journal Club. Practical considerations in HIV testing in the emergency department, characteristics of diagnostic tests, and the role of sensitivity analysis in observational studies (Answers to March 2008 Journal Club questions). Ann Emerg Med. 2008;52:170–181
  3. Guyatt GH, Sackett DL, Cook DJ Evidence-Based Medicine Working Group. Users' guides to the medical literature. II. How to use an article about therapy or prevention. B. What were the results and will they help me in caring for my patients?. JAMA. 1994;271:59–63
  4. Grobbee DE, Hoes AW. Clinical Epidemiology: Principles, Methods, and Applications for Clinical Research. Sudbury, MA: Jones and Bartlett; 2009;7-8
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  9. Barrett TW, Schriger DL Annals of Emergency Medicine Journal Club. Acutely decompensated heart failure in a county emergency department: a double-blind randomized controlled comparison of nesiritide versus placebo treatment (Answers to May 2008 Journal Club questions). Ann Emerg Med. 2008;51:571–578
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  15. Angell M. Drug companies and doctors: a story of corruption. N Y Rev Books. 2009;56:8–13
  16. Angell M. Industry-sponsored clinical research: a broken system. JAMA. 2008;300:1069–1071
  17. Bekelman JE, Li Y, Gross CP. Scope and impact of financial conflicts of interest in biomedical research: a systematic review. JAMA. 2003;289:454–465
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  19. Aronson S, Dyke CM, Stierer KA, et al. The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients. Anesth Analg. 2008;107:1111–1122

 Section editors: Tyler W. Barrett, MD; David L. Schriger, MD, MPH

 Editor's Note: These questions and answers refer to the Pollack et al article [Ann Emerg Med. 2009;53:329-338.] Readers should recognize that these are suggested answers and, although it is hoped that they are correct, are by no means comprehensive. There are many other points that could be made about these questions or about the article in general. Questions are rated “novice,” () “intermediate,” () and “advanced” ().

PII: S0196-0644(09)00108-5

doi: 10.1016/j.annemergmed.2009.01.026

Annals of Emergency Medicine
Volume 54, Issue 2 , Pages 301-307 , August 2009

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