Annals of Emergency Medicine
Volume 54, Issue 2 , Pages 171-180.e4, August 2009

Predictors of Emesis and Recovery Agitation With Emergency Department Ketamine Sedation: An Individual-Patient Data Meta-Analysis of 8,282 Children

  • Steven M. Green, MD

      Affiliations

    • Department of Emergency Medicine, Loma Linda University Medical Center and Children's Hospital, Loma Linda, CA
    • Corresponding Author InformationAddress for correspondence: Steven M. Green, MD, Department of Emergency Medicine, Loma Linda University Medical Center, 11234 Anderson St, Loma Linda, CA 92354; 805-969-2144, fax 775-307-4121
    • ,
  • Mark G. Roback, MD

      Affiliations

    • Department of Pediatrics, University of Minnesota, Minneapolis, MN
    • ,
  • Baruch Krauss, MD, EdM

      Affiliations

    • Division of Emergency Medicine, Children's Hospital and Harvard Medical School, Boston, MA
    • ,
  • Lance Brown, MD, MPH

      Affiliations

    • Department of Emergency Medicine, Loma Linda University Medical Center and Children's Hospital, Loma Linda, CA
    • ,
  • Ray G. McGlone, FCEM

      Affiliations

    • Royal Lancaster Infirmary, Lancaster, UK
    • ,
  • Dewesh Agrawal, MD

      Affiliations

    • Division of Emergency Medicine, Children's National Medical Center, Washington, DC
    • ,
  • Michele McKee, MD, MS

      Affiliations

    • Division of Emergency Medicine, Boston Medical Center, Boston, MA
    • ,
  • Markus Weiss, MD

      Affiliations

    • Department of Anaesthesia, University Children's Hospital, Zurich, Switzerland
    • ,
  • Raymond D. Pitetti, MD, MPH

      Affiliations

    • Division of Pediatric Emergency Medicine, Children's Hospital of Pittsburgh, PA
    • ,
  • Mark A. Hostetler, MD, MPH

      Affiliations

    • Department of Pediatrics, University of Chicago, Chicago, IL
    • ,
  • Joe E. Wathen, MD

      Affiliations

    • Department of Pediatrics, University of Colorado Health Sciences Center, Denver, CO
    • ,
  • Greg Treston, MBBS

      Affiliations

    • Emergency Department, Royal Darwin Hospital, Darwin, Northern Territory, Australia
    • ,
  • Barbara M. Garcia Pena, MD

      Affiliations

    • Division of Emergency Medicine, Miami Children's Hospital, Miami, FL
    • ,
  • Andreas C. Gerber, MD

      Affiliations

    • Department of Anaesthesia, University Children's Hospital, Zurich, Switzerland
    • ,
  • Joseph D. Losek, MD

      Affiliations

    • Department of Pediatrics, Medical University of South Carolina, Charleston, SC
    • ,
  • Emergency Department Ketamine Meta-Analysis Study Group

      Affiliations

    • All members are listed in the Appendix.

Received 27 January 2009; received in revised form 13 March 2009; accepted 1 April 2009. published online 08 June 2009.

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 Provide feedback for this article at the journal's Web site, www.annemergmed.com.

 Supervising editors: Kathy N. Shaw, MD, MSCE; Michael L. Callaham, MD

 Dr. Shaw and Dr. Callaham were the supervising editors on this article. Dr. Green did not participate in the editorial review or decision to publish this article.

 Author contributions: SMG conceived and designed the study. The methodology was critiqued and revised with extensive input from MGR, BK, LB, DA, RDP, JEW, and GT. All authors reviewed and recoded their data to comply with study definitions, and before data analysis the study protocol was critiqued and refined by all authors. SMG performed the data analysis, and a writing committee composed of SMG, MGR, and BK then created the article. All authors critiqued the draft and there were substantial revisions. SMG takes responsibility for the paper as a whole.

 Funding and support: By Annals policy, all authors are required to disclose any and all commercial, financial, and other relationships in any way related to the subject of this article that might create any potential conflict of interest. The authors have stated that no such relationships exist. See the Manuscript Submission Agreement in this issue for examples of specific conflicts covered by this statement.

 Publication date: Available online June 6, 2009.

 Reprints not available from the authors.

PII: S0196-0644(09)00372-2

doi:10.1016/j.annemergmed.2009.04.004

Annals of Emergency Medicine
Volume 54, Issue 2 , Pages 171-180.e4, August 2009

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