Annals of Emergency Medicine
Volume 54, Issue 3 , Pages 404-408 , September 2009

Clinical and ECG Effects of Escitalopram Overdose

  • Freek van Gorp

      Affiliations

    • Department of Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands
    • Department of Clinical Toxicology and Pharmacology, Calvary Mater Newcastle, Newcastle, Australia
    • ,
  • Ian M. Whyte, MBBS, FRACP, FRCPE

      Affiliations

    • Department of Clinical Toxicology and Pharmacology, Calvary Mater Newcastle, Newcastle, Australia
    • Discipline of Clinical Pharmacology, Faculty of Health, University of Newcastle, Darwin, Australia
    • ,
  • Geoffrey K. Isbister, MD, BSc, FACEM

      Affiliations

    • Department of Clinical Toxicology and Pharmacology, Calvary Mater Newcastle, Newcastle, Australia
    • Discipline of Clinical Pharmacology, Faculty of Health, University of Newcastle, Darwin, Australia
    • Menzies School of Health Research, Charles Darwin University, Darwin, Australia
    • Corresponding Author InformationAddress for correspondence: Geoffrey K. Isbister, MD, BSc, FACEM, Department of Clinical Toxicology, Calvary Mater Newcastle, Edith St, Waratah NSW 2298, Australia; 612-4921-1211, fax: 612-4921-1870

Received 30 January 2009 ,Revised 31 March 2009 ,Accepted 17 April 2009.

References 

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  3. Scharko AM, Schumacher J. Prolonged QTc interval in a 14-year-old girl with escitalopram overdose. J Child Adolesc Psychopharmacol. 2008;18:297–298
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  17. Isbister GK, Friberg LE, Hackett LP, et al. Pharmacokinetics of quetiapine in overdose and the effect of activated charcoal. Clin Pharmacol Ther. 2007;81:821–827
  18. Eddleston M, Eyer P, Worek F, et al. Differences between organophosphorus insecticides in human self-poisoning: a prospective cohort study. Lancet. 2005;366:1452–1459
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  21. Isbister GK. Electrocardiogram changes and arrhythmias in venlafaxine overdose. Br J Clin Pharmacol. 2009;67:572–576

 Supervising editor: Richard C. Dart, MD, PhD

 Author contributions: GKI designed the study with the assistance of FVG. IMW designed the database. FVG extracted the data. FVG and GKI undertook the analysis. FVG and GKI wrote the article, and IMW reviewed drafts. GKI takes responsibility for the paper as a whole.

 Funding and support: By Annals policy, all authors are required to disclose any and all commercial, financial, and other relationships in any way related to the subject of this article that might create any potential conflict of interest. See the Manuscript Submission Agreement in this issue for examples of specific conflicts covered by this statement. Dr. Isbister is funded by an NHMRC Clinical Career Development Award ID300785.

 Reprints not available from the authors.

 Publication date: Available online June 25, 2009.

PII: S0196-0644(09)00407-7

doi: 10.1016/j.annemergmed.2009.04.016

Annals of Emergency Medicine
Volume 54, Issue 3 , Pages 404-408 , September 2009

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