Annals of Emergency Medicine
Volume 55, Issue 4 , Pages 307-315.e1 , April 2010

Clinical Features From the History and Physical Examination That Predict the Presence or Absence of Pulmonary Embolism in Symptomatic Emergency Department Patients: Results of a Prospective, Multicenter Study

Presented at the Society for Academic Emergency Medicine annual meeting, May 31, 2008, Washington, DC.

  • D. Mark Courtney, MD

      Affiliations

    • Department of Emergency Medicine, Northwestern University, Chicago, IL
    • ,
  • Jeffrey A. Kline, MD

      Affiliations

    • Department of Emergency Medicine, Carolinas Medical Center, Charlotte, NC
    • Corresponding Author InformationAddress for correspondence: Jeffrey A. Kline, MD, Department of Emergency Medicine, Carolinas Medical Center, 1000 Blythe Boulevard. Charlotte NC, 28203; 704-355-3658, Fax 704-355-7047
    • ,
  • Christopher Kabrhel, MD, MPH

      Affiliations

    • Department of Emergency Services, Massachusetts General Hospital, Boston, MA
    • ,
  • Christopher L. Moore, MD

      Affiliations

    • Department of Emergency Medicine, Yale University Medical Center, New Haven, CT
    • ,
  • Howard A. Smithline, MD

      Affiliations

    • Department of Emergency Medicine, Baystate Medical Center, Springfield MA
    • ,
  • Kristen E. Nordenholz, MD

      Affiliations

    • Department of Surgery, Division of Emergency Medicine, University of Colorado School of Health Sciences, Denver, CO
    • ,
  • Peter B. Richman, MD, MBA

      Affiliations

    • Department of Emergency Medicine, Mayo Clinic Arizona, Scottsdale, AZ
    • ,
  • Michael C. Plewa, MD

      Affiliations

    • Department of Emergency Medicine, St. Vincent Mercy Medical Center, Toledo, OH

Received 4 August 2009 ,Revised 31 October 2009 ,Accepted 6 November 2009.

  • Image Result

    Theoretical construct of the test versus no test decision. DVT, Deep venous thrombosis; PE, pulmonary embolism.

    Theoretical construct of the test versus no test decision. DVT, Deep venous thrombosis; PE, pulmonary embolism.

  • Image Result

    Flow diagram showing diagnostic outcome of all patients. The study design did not allow for patients to have an endpoint of lost to follow-up.

    Flow diagram showing diagnostic outcome of all patients. The study design did not allow for patients to have an endpoint of lost to follow-up.

 Supervising editor: Steven M. Green, MD

 Author contributions: DMC and JAK participated in the conception and organization of the study. DMC, JAK, CK, CLM, HAS, KEN, PBR, and MCP participated in data collection and analysis and drafting and revising the article. DMC, JAK, CK, CLM, HAS, PBR, and MCP obtained funding. DMC, CK, CLM, HAS, PBR, and MCP participated in the writing of the study protocol. JAK had access to all the data in the study. DMC takes responsibility for the paper as a whole.

 Funding and support: By Annals policy, all authors are required to disclose any and all commercial, financial, and other relationships in any way related to the subject of this article that might create any potential conflict of interest. See the Manuscript Submission Agreement in this issue for examples of specific conflicts covered by this statement. National Institutes of Health grants 5K23HL077404(01-05) and 1K23HL077404-01 (Dr. Courtney) and 2R42HL074415-02A1, 5R42HL074415-03, R41HL074415, R42HL074415, and R01HL074384 (Dr. Kline).

 Publication date: Available online January 1, 2010.

 Reprints not available from the authors.

 Please see page 308 for the Editor's Capsule Summary of this article.

 Provide feedback on this article at the journal's Web site, www.annemergmed.com.

PII: S0196-0644(09)01735-1

doi: 10.1016/j.annemergmed.2009.11.010

Annals of Emergency Medicine
Volume 55, Issue 4 , Pages 307-315.e1 , April 2010

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