Annals of Emergency Medicine
Volume 55, Issue 6 , Pages 544-552.e3 , June 2010

The Importance of “Shrinkage” in Subgroup Analyses

Presented as an abstract at the Ambulatory Pediatric Association Region IX and X meeting, February 1998, Carmel, CA; and an abstract at the annual meeting of the Society for Academic Emergency Medicine, May 1998, Chicago, IL.

  • Ari M. Lipsky, MD, PhD

      Affiliations

    • Department of Emergency Medicine, Harbor–UCLA Medical Center, Torrance, CA
    • Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA
    • Los Angeles Biomedical Research Institute, Torrance, CA
    • Gertner Institute for Epidemiology and Health Policy Research, Tel Hashomer, Israel
    • Corresponding Author InformationAddress for correspondence: Ari M. Lipsky, MD, PhD, Department of Emergency Medicine, Box 21, Harbor–UCLA Medical Center, 1000 West Carson St, Torrance, CA 90509; 310-222-3501, fax 310-782-1763
  • ,
  • Marianne Gausche-Hill, MD

      Affiliations

    • Department of Emergency Medicine, Harbor–UCLA Medical Center, Torrance, CA
    • Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA
    • Los Angeles Biomedical Research Institute, Torrance, CA
  • ,
  • Muna Vienna, MD

      Affiliations

    • Department of Emergency Medicine, Harbor–UCLA Medical Center, Torrance, CA
  • ,
  • Roger J. Lewis, MD, PhD

      Affiliations

    • Department of Emergency Medicine, Harbor–UCLA Medical Center, Torrance, CA
    • Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA
    • Los Angeles Biomedical Research Institute, Torrance, CA

Received 18 February 2009 ,Revised 10 November 2009 ,Accepted 4 January 2010.

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 Supervising editor: Robert L. Wears, MD, MS

 Author contributions: MG-H and RJL conceived the study. AML, MV, and RJL analyzed the data. AML drafted the article, and all authors contributed substantially to its revision. AML takes responsibility for the paper as a whole.

 Funding and support: By Annals policy, all authors are required to disclose any and all commercial, financial, and other relationships in any way related to the subject of this article that might create any potential conflict of interest. See the Manuscript Submission Agreement in this issue for examples of specific conflicts covered by this statement. This publication was made possible by grant 1F32RR022167 from the National Center for Research Resources (NCRR), a component of the National Institutes of Health (NIH). Its contents are solely the responsibility of the authors and do not necessarily represent the official view of the NCRR or NIH. This work was previously supported by a Research Fellowship Grant from the Emergency Medicine Foundation to AML. The conduct and data analysis of the Pediatric Airway Management Project was supported by grant HS-09065-01 from the Agency for Healthcare Research and Quality, grant EMS-3036 from the State of California Emergency Medical Services Authority, and grant MCH064004-01-0 from the Bureau for Maternal and Child Health of the Public Health Service.

 Reprints not available from the authors.

 Please see page 545 for the Editor's Capsule Summary of this article.

 Publication date: Available online February 5, 2010.

PII: S0196-0644(10)00005-3

doi: 10.1016/j.annemergmed.2010.01.002

Annals of Emergency Medicine
Volume 55, Issue 6 , Pages 544-552.e3 , June 2010