Annals of Emergency Medicine
Volume 56, Issue 2 , Pages 188-200 , August 2010

Is the Golden Hour Tarnished? Registries and Multivariable Regression: Answers to the March 2010 Journal Club Questions

References 

  1. Burton A, Altman DG. Missing covariate data within cancer prognostic studies: a review of current reporting and proposed guidelines. Br J Cancer. 2004;91:4–8
  2. Newgard CD, Schmicker RH, Hedges JR, et al. Emergency medical services intervals and survival in trauma: assessment of the “golden hour” in a North American prospective cohort. Ann Emerg Med. 2010;55:235–246e234
  3. Donders AR, van der Heijden GJ, Stijnen T, et al. Review: a gentle introduction to imputation of missing values. J Clin Epidemiol. 2006;59:1087–1091
  4. Steyerberg EW. Clinical Prediction Models: A Practical Approach to Development, Validation, and Updating. New York, NY: Springer; 2009;
  5. Allison PD. Missing data. In:  Lewis-Beck MS editors. Sage University Papers Series on Quantitative Applications in the Social Sciences: No. 07-136. Thousand Oaks, CA: Sage Publications; 2001;p. 1–12
  6. Harrell FE. Regression Modeling Strategies: With Applications to Linear Models, Logistic Regression, and Survival Analysis. New York, NY: Springer; 2001;
  7. Schafer JL. Analysis of Incomplete Multivariate Data. New York, NY: Chapman & Hall; 1997;
  8. de Groot JA, Janssen KJ, Zwinderman AH, et al. Multiple imputation to correct for partial verification bias revisited. Stat Med. 2008;27:5880–5889
  9. Janssen KJ, Vergouwe Y, Donders AR, et al. Dealing with missing predictor values when applying clinical prediction models. Clin Chem. 2009;55:994–1001
  10. van der Heijden GJ, Donders AR, Stijnen T, et al. Imputation of missing values is superior to complete case analysis and the missing-indicator method in multivariable diagnostic research: a clinical example. J Clin Epidemiol. 2006;59:1102–1109
  11. Moylan JA. Impact of helicopters on trauma care and clinical results. Ann Surg. 1988;208:673–678
  12. Neel SH. Helicopter evacuation in Korea. U S Armed Forces Med J. 1955;6:691–702
  13. Neel S. Army aeromedical evacuation procedures in Vietnam: implications for rural America. JAMA. 1968;204:309–313
  14. Law DK, Law JK, Brennan R, et al. Trauma operating room in conjunction with an air ambulance system: indications, interventions, and outcomes. J Trauma. 1982;22:759–765
  15. Cleveland HC, Bigelow DB, Dracon D, et al. A civilian air emergency service: a report of its development, technical aspects, and experience. J Trauma. 1976;16:452–463
  16. Topol EJ, Fung AY, Kline E, et al. Safety of helicopter transport and out-of-hospital intravenous fibrinolytic therapy in patients with evolving myocardial infarction. Cathet Cardiovasc Diagn. 1986;12:151–155
  17. Abernethy M, Bledsoe B, Carrison D. Can emergency physicians fix the helicopter EMS system?. Emergency Physicians Monthly. 2010;Vol 17:http://www.epmonthly.com/features/current-features/can-eps-fix-the-helicopter-ems-system?/Accessed April 19, 2010
  18. EMS Committee. Appropriate utilization of air medical transport in the out-of-hospital setting. Ann Emerg Med. 1999;34:420
  19. Air ambulance medical transport advertising and marketing. Ann Emerg Med. 2008;52:580–581
  20. Talving P, Teixeira PG, Barmparas G, et al. Helicopter evacuation of trauma victims in Los Angeles: does it improve survival?. World J Surg. 2009;33:2469–2476
  21. Ringburg AN, Spanjersberg WR, Frankema SP, et al. Helicopter emergency medical services (HEMS): impact on on-scene times. J Trauma. 2007;63:258–262
  22. Biewener A, Aschenbrenner U, Rammelt S, et al. Impact of helicopter transport and hospital level on mortality of polytrauma patients. J Trauma. 2004;56:94–98
  23. Buntman AJ, Yeomans KA. The effect of air medical transport on survival after trauma in Johannesburg, South Africa. S Afr Med J. 2002;92:807–811
  24. Di Bartolomeo S, Sanson G, Nardi G, et al. HEMS vs. Ground-BLS care in traumatic cardiac arrest. Prehosp Emerg Care. 2005;9:79–84
  25. Newgard CD, McConnell KJ, Hedges JR, et al. The benefit of higher level of care transfer of injured patients from nontertiary hospital emergency departments. J Trauma. 2007;63:965–971
  26. Peth HA. The Emergency Medical Treatment and Active Labor Act (EMTALA): guidelines for compliance. Emerg Med Clin North Am. 2004;22:225–240
  27. Centers for Medicare & Medicaid Services. State operations manual appendix V—interpretive guidelines—responsibilities of Medicare participating hospitals in emergency cases. http://www.cms.hhs.gov/manuals/Downloads/som107ap_v_emerg.pdfAccessed December 22, 2009
  28. McConnell KJ, Newgard CD, Mullins RJ, et al. Mortality benefit of transfer to level I versus level II trauma centers for head-injured patients. Health Serv Res. 2005;40:435–457
  29. Cudnik MT, Newgard CD, Sayre MR, et al. Level I versus level II trauma centers: an outcomes-based assessment. J Trauma. 2009;66:1321–1326
  30. Koval KJ, Tingey CW, Spratt KF. Are patients being transferred to level-I trauma centers for reasons other than medical necessity?. J Bone Joint Surg Am. 2006;88:2124–2132
  31. Spain DA, Bellino M, Kopelman A, et al. Requests for 692 transfers to an academic level I trauma center: implications of the emergency medical treatment and active labor act. J Trauma. 2007;62:63–67discussion 67-68
  32. Cooper RJ. Misleading negative chest radiographs: should we ADHERE to the conclusions?. Ann Emerg Med. 2006;47:19–21
  33. Izquierdo JN, Schoenbach VJ. The potential and limitations of data from population-based state cancer registries. Am J Public Health. 2000;90:695–698
  34. Gilbert EH, Lowenstein SR, Koziol-McLain J, et al. Chart reviews in emergency medicine research: where are the methods?. Ann Emerg Med. 1996;27:305–308
  35. Newgard CD, Sears GK, Rea TD, et al. The Resuscitation Outcomes Consortium Epistry–Trauma: design, development, and implementation of a North American epidemiologic prehospital trauma registry. Resuscitation. 2008;78:170–178
  36. Barrett TW, Schriger DL Annals of Emergency Medicine Journal Club. Measures of emergency department crowding, odds ratios, and the dangers of making continuous data categorical (Answers to January 2008 journal club questions). Ann Emerg Med. Jun 2008;51:782–789
  37. Royston P, Altman DG. Regression using fractional polynomials of continuous covariates: parsimonious parametric modelling. Journal of the Royal Statistical Society. Series C (Applied Statistics). 1994;43:429–467
  38. Wears RL. Advanced statistics: statistical methods for analyzing cluster and cluster-randomized data. Acad Emerg Med. 2002;9:330–341
  39. Grady D, Hearst N. Utilizing existing databases. In:  Hulley S,  Cummings S, Browner , et al. editor. Designing Clinical Research. 3rd ed.. Philadelphia, PA: Lippincott Williams & Wilkins; 2007;p. 220

 Section editors: Tyler W. Barrett, MD; David L. Schriger, MD, MPH

 Editor's Note: You are reading the 14th installment of Annals of Emergency Medicine Journal Club. The questions and the article they are about (Newgard et al. Ann Emerg Med. 2010;55:235-246) were published in the March 2010 issue.

 Information about journal club can be found at http://www.annemergmed.com/content/journalclub.

 Readers should recognize that these are suggested answers. We hope they are accurate; we know that they are not comprehensive. There are many other points that could be made about these questions or about the article in general. Questions are rated “novice,” () “intermediate,” () and “advanced” () so that individuals planning a journal club can assign the right question to the right student. The “novice” rating does not imply that a novice should be able to spontaneously answer the question. “Novice” means we expect that someone with little background should be able to do a bit of reading, formulate an answer, and teach the material to others. Intermediate and advanced questions also will likely require some reading and research, and that reading will be sufficiently difficult that some background in clinical epidemiology will be helpful in understanding the reading and concepts.

 We are interested in receiving feedback about this feature. Please journalclub@acep.org with your comments.

PII: S0196-0644(10)00352-5

doi: 10.1016/j.annemergmed.2010.04.003

Annals of Emergency Medicine
Volume 56, Issue 2 , Pages 188-200 , August 2010

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