Annals of Emergency Medicine
Volume 30, Issue 1 , Pages 40-44 , July 1997

Thrombocytopenia Following Timber Rattlesnake Envenomation

Received 7 April 1997 ,Accepted 24 April 1997.

References 

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  3. Straight RC, Glenn JL, Wolt TB, et al.  Regional differences in content of small basic peptide toxins in the venoms of Crotalus adamanteus and Crotalus horridus. Comp Biochem Physiol C Pharmacol Toxicol Endocrinol. 1991;100:51–58
  4. Smith MS, Ownby CL. Ability of polyvalent (Crotalidae) antivenin to neutralize myonecrosis, hemorrhage and lethality induced by timber rattlesnake (Crotalus horridus horridus) venom. Toxicon. 1985;23:409–424
  5. Jansen PW, Perkin RM, Van Stralen D. Mojave rattlesnake envenomation: Prolonged neurotoxicity and rhabdomyolysis. Ann Emerg Med. 1992;21:322–325
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  8. Tallon RW, Koch KL, Barnes SG, et al.  Correspondence. N Engl J Med. 1981;305:1347–1348
  9. Schmaier AH, Claypool W, Colman RW. Crotalocytin: Recognition and purification of a timber rattlesnake platelet activating protein. Blood. 1980;56:1013–1019
  10. Burgess JL, Dart RC. Snake venom coagulopathy and abuse of blood products in the treatment of pit viper envenomation. Ann Emerg Med. 1991;20:795–801
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  15. Pirkle H, Stocker K. Thrombin like enzymes from snake venoms: An inventory. Thromb Haemost. 1991;65:440–450
  16. Bonilla CA. Defibrinating enzyme from timber rattlesnake (Crotalus horridus horridus) venom: A potential agent for therapeutic defibrination. Thromb Res. 1975;6:151–169
  17. Riffer E, Curry SC, Gerkin R. Successful treatment with antivenin of marked thrombocytopenia without significant coagulopathy following rattlesnake bites. Ann Emerg Med. 1987;16:1297–1299
  18. Schmaier AH, Colman RW. Crotalocytin: Characterization of the timber rattlesnake platelet activating protein. Blood. 1980;56:1020–1028
  19. Longenecker GL. Effects of snake venoms on blood platelets. In:  Tu AT editors. Reptile Venoms and Toxins. 5:New York: Marcel Dekker; 1991;p. 189–224

☆ From the Departments of Emergency Medicine and Pediatrics, University of Virginia, Charlottesville, VA;* and the Central Pennsylvania Poison Center‡ and the Center for Emergency Medical Services,§ Milton S Hershey Medical Center, Pennsylvania State University, Hershey, PA.

☆☆ Reprint no. 47/1/82828

★ Reprints not available from the authors.

PII: S0196-0644(97)70108-2

Annals of Emergency Medicine
Volume 30, Issue 1 , Pages 40-44 , July 1997

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