Annals of Emergency Medicine
Volume 33, Issue 2 , Pages 141-146 , February 1999

Use of Heliox-Driven Nebulizer Therapy in the Treatment of Acute Asthma

Received 17 June 1998 ,Revised 1 October 1998 ,Accepted 19 October 1998.

References 

  1. McGee DL, Wald DA, Hinchliffe S. Helium-oxygen therapy in the emergency department. J Emerg Med. 1997;15:291–296
  2. Madison JM, Irwin RS. Heliox for asthma: A trial balloon. Chest. 1995;107:597–598
  3. Skrinskas GJ, Hyland RH, Hutcheon MA. Using helium-oxygen mixtures in the management of acute upper airway obstruction. Can Med Assoc J. 1983;128:555–558
  4. Manthous CA. Management of severe exacerbations of asthma. Am J Med. 1995;99:298–308
  5. Clinical Practice Guidelines . Guidelines for the Diagnosis and Management of Asthma. Bethesda, MD: National Institutes of Health; 1997; Publication No. 97-4051
  6. Bailey WC, Wilson SR, Weiss KB, et al.  Measures for use in asthma clinical research. Am J Respir Crit Care Med. 1994;149:S1–S8
  7. Jagoda A, Sheperd SM, Spevitz A, et al.  Refractory asthma: Part 1. Epidemiology, pathophysiology, pharmacologic interventions. Ann Emerg Med. 1997;29:262–274
  8. In: ed 3.  Gershwin M,  Halpern GM editor. Bronchial Asthma: Principles of Diagnosis and Treatment. Totowa, NJ: Humana Press; 1994;p. 301
  9. Boorstein JM, Boorstein SM, Humphries GN, et al.  Using helium-oxygen mixtures in the emergency management of acute upper airway obstruction. Ann Emerg Med. 1989;18:688–690
  10. Kass JE, Castriotta RJ. Heliox therapy in acute severe asthma. Chest. 1995;107:757–760
  11. Fleming MD, Weigelt JA, Brewer V, et al.  Effect of helium and oxygen on airflow in a narrowed airway. Arch Surg. 1992;127:956–960
  12. Houck JR, Keamy MF, McDonough JM. Effect of helium concentration on experimental upper airway obstruction. Ann Otol Rhinol Laryngol. 1990;99:556–561
  13. Papamoschou D. Theoretical validation of the respiratory benefits of helium-oxygen mixtures. Respiration Physiol. 1995;99:183–190
  14. Anderson M, Svartengren M, Bylin G, et al.  Deposition in asthmatics of particles inhaled in air or in helium-oxygen. Am Rev Respir Dis. 1993;147:524–528
  15. Austan F, Camden NJ. Heliox inhalation in status asthmaticus and respiratory acidemia: A brief report. Heart Lung. 1996;25:155–157
  16. Gluck EH, Onorato DJ, Castriotta R. Helium-oxygen mixtures in intubated patients with status asthmaticus and respiratory acidosis. Chest. 1990;98:693–698
  17. Shiue ST, Gluck EH. The use of helium-oxygen mixtures in the support of patients with status asthmaticus and respiratory acidosis. J Asthma. 1989;26:177–180

☆ Address for reprints:Sean O Henderson, MD, Department of Emergency Medicine, University of Southern California School of Medicine, LAC/USC Medical Center, Unit 1, Room 1011, 1200 North State Street, Los Angeles, CA 90033; 213-226-6667, fax 213-226-8044.

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Annals of Emergency Medicine
Volume 33, Issue 2 , Pages 141-146 , February 1999

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